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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3C All Species: 9.09
Human Site: T1064 Identified Species: 14.29
UniProt: Q15386 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15386 NP_055486.2 1083 123923 T1064 L P E F Y D E T L L R S K L L
Chimpanzee Pan troglodytes XP_528010 1089 124652 T1070 L P E F Y D E T L L R S K L L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539937 1088 124202 T1069 L P E F Y D E T L L R S K L L
Cat Felis silvestris
Mouse Mus musculus Q80U95 1083 123957 A1064 L P E F Y D E A L L R S K L L
Rat Rattus norvegicus Q62940 887 102376 L869 P Y E S F D E L W D K L Q M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510756 1084 124281 N1065 L P E F Y D E N L L R S K L L
Chicken Gallus gallus NP_001026138 1084 124128 N1065 L P E F Y D E N L M R S K L L
Frog Xenopus laevis Q6DCL5 944 106566 L926 E Y P S K E I L K D R L L V A
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 K747 P P Y E S Y D K L Y D K L L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611896 1122 128925 E1103 L P P F K T V E Q M R E K L L
Honey Bee Apis mellifera XP_396547 1033 119022 K1014 L P E F P D E K T L R E K L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797123 1037 118587 E1018 L P E F S D E E T L R E K L L
Poplar Tree Populus trichocarpa XP_002314972 1027 117409 E1008 L P P Y R S K E Q L A T K L L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 E1010 L P P Y Q S K E L L E T K L M
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 I892 P D Y R N K T I L R E K L L Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 N.A. 95.4 N.A. 93.3 22.1 N.A. 91.4 90.6 22.8 22.5 N.A. 39.7 43 N.A. 44.2
Protein Similarity: 100 98.1 N.A. 97.4 N.A. 97.2 38.4 N.A. 95.6 94.8 39 38.3 N.A. 61 62.7 N.A. 61.6
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 20 N.A. 93.3 86.6 6.6 20 N.A. 46.6 73.3 N.A. 73.3
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 46.6 N.A. 93.3 93.3 20 26.6 N.A. 53.3 73.3 N.A. 73.3
Percent
Protein Identity: 28.3 N.A. N.A. 28.7 26.7 N.A.
Protein Similarity: 47 N.A. N.A. 49 44.9 N.A.
P-Site Identity: 40 N.A. N.A. 40 13.3 N.A.
P-Site Similarity: 60 N.A. N.A. 66.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 60 7 0 0 14 7 0 0 0 0 % D
% Glu: 7 0 60 7 0 7 60 27 0 0 14 20 0 0 0 % E
% Phe: 0 0 0 60 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 14 7 14 14 7 0 7 14 74 0 0 % K
% Leu: 74 0 0 0 0 0 0 14 60 60 0 14 20 87 67 % L
% Met: 0 0 0 0 0 0 0 0 0 14 0 0 0 7 7 % M
% Asn: 0 0 0 0 7 0 0 14 0 0 0 0 0 0 0 % N
% Pro: 20 80 27 0 7 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 0 0 14 0 0 0 7 0 0 % Q
% Arg: 0 0 0 7 7 0 0 0 0 7 67 0 0 0 0 % R
% Ser: 0 0 0 14 14 14 0 0 0 0 0 40 0 0 0 % S
% Thr: 0 0 0 0 0 7 7 20 14 0 0 14 0 0 7 % T
% Val: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 14 14 14 40 7 0 0 0 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _