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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3C All Species: 24.24
Human Site: T582 Identified Species: 38.1
UniProt: Q15386 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15386 NP_055486.2 1083 123923 T582 A F Q S I G V T T S S E M Q Q
Chimpanzee Pan troglodytes XP_528010 1089 124652 T588 A F Q S I G V T T S S E M Q Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539937 1088 124202 T587 A F Q S I G V T T N S E M Q Q
Cat Felis silvestris
Mouse Mus musculus Q80U95 1083 123957 T582 A F Q S I G V T T N S E M Q Q
Rat Rattus norvegicus Q62940 887 102376 T451 P A H L R G K T P V D S N D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510756 1084 124281 T583 A F R S V G V T T N S E M Q Q
Chicken Gallus gallus NP_001026138 1084 124128 T583 A F R S V G V T K N T E M Q Q
Frog Xenopus laevis Q6DCL5 944 106566 S508 Q M P Q G M T S P R F I E F V
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 R329 T T Q F T D P R L S A N L H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611896 1122 128925 D628 L G H T E A D D K K L R H Q K
Honey Bee Apis mellifera XP_396547 1033 119022 Q572 H M R D L R R Q F C P E G H W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797123 1037 118587 R575 L I K Q L H S R D I R R P F C
Poplar Tree Populus trichocarpa XP_002314972 1027 117409 A566 K L V K N T S A Y N G N P V E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 S565 P N T G K S V S N D L S K K N
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 D474 M E K E I D L D K E R P P L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 N.A. 95.4 N.A. 93.3 22.1 N.A. 91.4 90.6 22.8 22.5 N.A. 39.7 43 N.A. 44.2
Protein Similarity: 100 98.1 N.A. 97.4 N.A. 97.2 38.4 N.A. 95.6 94.8 39 38.3 N.A. 61 62.7 N.A. 61.6
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 13.3 N.A. 80 66.6 0 13.3 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 13.3 N.A. 100 93.3 6.6 26.6 N.A. 20 20 N.A. 13.3
Percent
Protein Identity: 28.3 N.A. N.A. 28.7 26.7 N.A.
Protein Similarity: 47 N.A. N.A. 49 44.9 N.A.
P-Site Identity: 0 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 7 0 0 0 7 0 7 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % C
% Asp: 0 0 0 7 0 14 7 14 7 7 7 0 0 7 0 % D
% Glu: 0 7 0 7 7 0 0 0 0 7 0 47 7 0 7 % E
% Phe: 0 40 0 7 0 0 0 0 7 0 7 0 0 14 0 % F
% Gly: 0 7 0 7 7 47 0 0 0 0 7 0 7 0 0 % G
% His: 7 0 14 0 0 7 0 0 0 0 0 0 7 14 0 % H
% Ile: 0 7 0 0 34 0 0 0 0 7 0 7 0 0 0 % I
% Lys: 7 0 14 7 7 0 7 0 20 7 0 0 7 7 14 % K
% Leu: 14 7 0 7 14 0 7 0 7 0 14 0 7 7 14 % L
% Met: 7 14 0 0 0 7 0 0 0 0 0 0 40 0 0 % M
% Asn: 0 7 0 0 7 0 0 0 7 34 0 14 7 0 7 % N
% Pro: 14 0 7 0 0 0 7 0 14 0 7 7 20 0 0 % P
% Gln: 7 0 34 14 0 0 0 7 0 0 0 0 0 47 40 % Q
% Arg: 0 0 20 0 7 7 7 14 0 7 14 14 0 0 0 % R
% Ser: 0 0 0 40 0 7 14 14 0 20 34 14 0 0 0 % S
% Thr: 7 7 7 7 7 7 7 47 34 0 7 0 0 0 0 % T
% Val: 0 0 7 0 14 0 47 0 0 7 0 0 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _