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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3C
All Species:
23.64
Human Site:
Y181
Identified Species:
37.14
UniProt:
Q15386
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15386
NP_055486.2
1083
123923
Y181
V
F
S
S
E
N
T
Y
L
P
V
L
Q
D
A
Chimpanzee
Pan troglodytes
XP_528010
1089
124652
Y187
V
F
S
S
E
S
T
Y
L
P
V
L
Q
D
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539937
1088
124202
Y181
V
F
S
S
E
N
T
Y
L
P
V
L
H
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80U95
1083
123957
Y181
V
F
T
S
E
N
T
Y
L
P
V
L
Q
D
S
Rat
Rattus norvegicus
Q62940
887
102376
T61
E
E
E
H
V
L
F
T
A
E
S
I
I
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510756
1084
124281
Y181
V
F
S
S
E
N
T
Y
F
P
V
L
Q
D
A
Chicken
Gallus gallus
NP_001026138
1084
124128
Y181
V
F
S
S
E
N
T
Y
L
P
V
L
Q
D
V
Frog
Xenopus laevis
Q6DCL5
944
106566
L118
K
K
C
M
S
K
L
L
E
Y
N
A
D
V
N
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611896
1122
128925
V174
T
F
T
T
V
S
S
V
Q
Q
Y
M
K
D
E
Honey Bee
Apis mellifera
XP_396547
1033
119022
Y174
Y
L
R
N
I
F
I
Y
L
I
K
H
K
Y
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797123
1037
118587
R180
L
R
G
F
I
N
E
R
L
P
P
G
I
D
V
Poplar Tree
Populus trichocarpa
XP_002314972
1027
117409
L174
R
K
Q
L
K
D
Q
L
V
M
V
P
R
D
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWB8
1029
117643
V175
R
L
R
D
Q
L
L
V
T
P
E
E
A
S
I
Baker's Yeast
Sacchar. cerevisiae
P53119
910
105547
L84
I
P
A
Y
G
G
K
L
I
Y
Y
I
S
Q
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
N.A.
95.4
N.A.
93.3
22.1
N.A.
91.4
90.6
22.8
22.5
N.A.
39.7
43
N.A.
44.2
Protein Similarity:
100
98.1
N.A.
97.4
N.A.
97.2
38.4
N.A.
95.6
94.8
39
38.3
N.A.
61
62.7
N.A.
61.6
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
86.6
0
N.A.
93.3
93.3
0
0
N.A.
13.3
13.3
N.A.
26.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
13.3
N.A.
93.3
93.3
0
0
N.A.
53.3
26.6
N.A.
33.3
Percent
Protein Identity:
28.3
N.A.
N.A.
28.7
26.7
N.A.
Protein Similarity:
47
N.A.
N.A.
49
44.9
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
7
0
0
7
7
0
27
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
7
0
0
0
0
0
0
7
60
0
% D
% Glu:
7
7
7
0
40
0
7
0
7
7
7
7
0
0
7
% E
% Phe:
0
47
0
7
0
7
7
0
7
0
0
0
0
0
7
% F
% Gly:
0
0
7
0
7
7
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
7
7
0
0
% H
% Ile:
7
0
0
0
14
0
7
0
7
7
0
14
14
0
7
% I
% Lys:
7
14
0
0
7
7
7
0
0
0
7
0
14
0
0
% K
% Leu:
7
14
0
7
0
14
14
20
47
0
0
40
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
0
0
0
7
0
40
0
0
0
0
7
0
0
0
7
% N
% Pro:
0
7
0
0
0
0
0
0
0
54
7
7
0
0
0
% P
% Gln:
0
0
7
0
7
0
7
0
7
7
0
0
34
7
0
% Q
% Arg:
14
7
14
0
0
0
0
7
0
0
0
0
7
0
0
% R
% Ser:
0
0
34
40
7
14
7
0
0
0
7
0
7
14
20
% S
% Thr:
7
0
14
7
0
0
40
7
7
0
0
0
0
0
0
% T
% Val:
40
0
0
0
14
0
0
14
7
0
47
0
0
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
47
0
14
14
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _