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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGPT1
All Species:
26.67
Human Site:
Y462
Identified Species:
65.19
UniProt:
Q15389
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15389
NP_001137.2
498
57513
Y462
S
N
L
N
G
M
F
Y
T
A
G
Q
N
H
G
Chimpanzee
Pan troglodytes
XP_519904
419
48210
T384
N
L
N
G
M
F
Y
T
A
G
Q
N
H
G
K
Rhesus Macaque
Macaca mulatta
XP_001088871
498
57482
Y462
S
N
L
N
G
M
F
Y
T
A
G
Q
N
H
G
Dog
Lupus familis
XP_852012
498
55980
Y462
S
N
L
N
G
I
Y
Y
P
A
R
H
H
V
R
Cat
Felis silvestris
Mouse
Mus musculus
O08538
498
57486
Y462
S
N
L
N
G
M
F
Y
T
A
G
Q
N
H
G
Rat
Rattus norvegicus
O35460
497
57442
Y461
S
N
L
N
G
M
F
Y
T
A
G
Q
N
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506935
400
45919
T365
N
L
N
G
M
F
Y
T
A
G
Q
N
H
G
K
Chicken
Gallus gallus
XP_418382
498
57419
Y462
S
N
L
N
G
M
F
Y
S
A
G
Q
N
H
G
Frog
Xenopus laevis
Q6AX44
457
50990
G422
L
N
G
Q
Y
L
T
G
H
H
A
S
Y
A
D
Zebra Danio
Brachydanio rerio
NP_571888
513
58342
Y476
S
N
L
N
G
V
Y
Y
R
Q
G
Q
H
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.7
99.8
55
N.A.
97.5
96.9
N.A.
71
91.7
28.1
65.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.9
99.8
74.9
N.A.
99
98.3
N.A.
75
96.5
47.7
80.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
46.6
N.A.
100
100
N.A.
0
93.3
6.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
66.6
N.A.
100
100
N.A.
20
100
13.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
20
60
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
20
50
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
20
70
0
0
10
0
20
60
0
0
20
60
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
10
40
50
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% K
% Leu:
10
20
70
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
20
50
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
80
20
70
0
0
0
0
0
0
0
20
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
10
20
60
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% R
% Ser:
70
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
20
40
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
40
70
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _