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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHCR24
All Species:
26.06
Human Site:
S291
Identified Species:
40.95
UniProt:
Q15392
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15392
NP_055577.1
516
60101
S291
M
T
D
E
A
E
P
S
K
L
N
S
I
G
N
Chimpanzee
Pan troglodytes
XP_001153873
516
60069
S291
M
T
D
E
A
E
P
S
K
L
N
S
I
G
N
Rhesus Macaque
Macaca mulatta
XP_001108186
590
68025
S365
M
T
D
E
V
E
P
S
K
L
N
S
I
G
N
Dog
Lupus familis
XP_546693
516
59942
S291
M
T
D
D
A
E
P
S
K
L
N
S
I
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCH6
516
60094
S291
M
T
D
D
V
E
P
S
K
L
N
S
I
G
S
Rat
Rattus norvegicus
Q5BQE6
516
60029
S291
M
T
D
D
V
E
P
S
K
L
N
S
I
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517895
508
58237
D283
M
T
D
K
A
E
P
D
K
L
N
R
I
G
R
Chicken
Gallus gallus
NP_001026459
516
60104
S291
L
T
D
E
A
E
P
S
K
I
N
R
I
G
N
Frog
Xenopus laevis
NP_001086259
516
59787
G291
L
T
D
D
A
Q
A
G
Q
V
N
Q
I
G
Q
Zebra Danio
Brachydanio rerio
NP_001008645
516
60258
D291
M
T
D
H
A
E
P
D
K
T
N
C
I
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17397
525
61402
E300
D
G
P
D
T
H
D
E
V
V
N
P
I
G
R
Sea Urchin
Strong. purpuratus
XP_001202234
351
40719
F141
N
F
W
K
P
W
F
F
K
H
V
E
S
F
L
Poplar Tree
Populus trichocarpa
XP_002315056
563
65561
K298
Y
A
S
K
E
E
A
K
K
K
G
N
V
I
N
Maize
Zea mays
NP_001105560
562
64988
K296
Y
A
S
K
E
E
A
K
K
K
G
N
K
I
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39085
561
65376
K296
Y
A
S
K
E
E
A
K
K
K
G
N
K
I
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
86.9
96.9
N.A.
96.9
97
N.A.
77.1
78.2
78
79.4
N.A.
N.A.
N.A.
48.7
44.3
Protein Similarity:
100
100
87.2
98.8
N.A.
98.8
99
N.A.
84.1
89.9
90.3
90.6
N.A.
N.A.
N.A.
66.2
56.5
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
73.3
80
40
66.6
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
80
93.3
73.3
66.6
N.A.
N.A.
N.A.
33.3
13.3
Percent
Protein Identity:
38.5
38.7
N.A.
38.6
N.A.
N.A.
Protein Similarity:
57.1
57.4
N.A.
56.6
N.A.
N.A.
P-Site Identity:
20
20
N.A.
20
N.A.
N.A.
P-Site Similarity:
40
33.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
47
0
27
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
7
0
67
34
0
0
7
14
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
27
20
80
0
7
0
0
0
7
0
0
0
% E
% Phe:
0
7
0
0
0
0
7
7
0
0
0
0
0
7
0
% F
% Gly:
0
7
0
0
0
0
0
7
0
0
20
0
0
74
0
% G
% His:
0
0
0
7
0
7
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
74
20
0
% I
% Lys:
0
0
0
34
0
0
0
20
87
20
0
0
14
0
0
% K
% Leu:
14
0
0
0
0
0
0
0
0
47
0
0
0
0
7
% L
% Met:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
74
20
0
0
54
% N
% Pro:
0
0
7
0
7
0
60
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
7
0
0
7
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
14
% R
% Ser:
0
0
20
0
0
0
0
47
0
0
0
40
7
0
14
% S
% Thr:
0
67
0
0
7
0
0
0
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
20
0
0
0
7
14
7
0
7
0
0
% V
% Trp:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _