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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHCR24
All Species:
50
Human Site:
Y237
Identified Species:
78.57
UniProt:
Q15392
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15392
NP_055577.1
516
60101
Y237
R
I
I
P
A
K
K
Y
V
K
L
R
F
E
P
Chimpanzee
Pan troglodytes
XP_001153873
516
60069
Y237
R
I
I
P
A
K
K
Y
V
K
L
R
F
E
P
Rhesus Macaque
Macaca mulatta
XP_001108186
590
68025
Y311
R
I
I
P
A
K
K
Y
V
K
L
R
F
E
P
Dog
Lupus familis
XP_546693
516
59942
Y237
R
I
I
P
A
K
K
Y
V
K
L
R
F
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCH6
516
60094
Y237
R
I
I
P
A
K
K
Y
V
K
L
R
F
E
P
Rat
Rattus norvegicus
Q5BQE6
516
60029
Y237
R
I
I
P
A
K
K
Y
V
K
L
R
F
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517895
508
58237
Y229
R
I
I
P
A
K
K
Y
V
R
L
Q
Y
E
P
Chicken
Gallus gallus
NP_001026459
516
60104
Y237
K
M
I
P
A
K
K
Y
I
R
L
H
Y
E
P
Frog
Xenopus laevis
NP_001086259
516
59787
Y237
K
I
V
P
A
K
K
Y
V
K
L
H
Y
T
P
Zebra Danio
Brachydanio rerio
NP_001008645
516
60258
W237
R
I
I
P
A
Q
K
W
V
K
L
H
Y
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17397
525
61402
Y242
K
I
I
P
C
K
K
Y
V
K
L
T
Y
K
K
Sea Urchin
Strong. purpuratus
XP_001202234
351
40719
A91
D
D
V
S
N
V
F
A
K
C
S
K
E
A
Q
Poplar Tree
Populus trichocarpa
XP_002315056
563
65561
Y234
K
L
I
P
V
K
E
Y
M
R
L
T
Y
K
P
Maize
Zea mays
NP_001105560
562
64988
Y235
K
L
I
P
I
K
E
Y
M
K
L
T
Y
T
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39085
561
65376
Y235
R
L
I
K
V
K
E
Y
M
R
L
T
Y
I
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
86.9
96.9
N.A.
96.9
97
N.A.
77.1
78.2
78
79.4
N.A.
N.A.
N.A.
48.7
44.3
Protein Similarity:
100
100
87.2
98.8
N.A.
98.8
99
N.A.
84.1
89.9
90.3
90.6
N.A.
N.A.
N.A.
66.2
56.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
60
66.6
73.3
N.A.
N.A.
N.A.
60
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
86.6
93.3
N.A.
N.A.
N.A.
80
13.3
Percent
Protein Identity:
38.5
38.7
N.A.
38.6
N.A.
N.A.
Protein Similarity:
57.1
57.4
N.A.
56.6
N.A.
N.A.
P-Site Identity:
40
46.6
N.A.
40
N.A.
N.A.
P-Site Similarity:
86.6
80
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
67
0
0
7
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
20
0
0
0
0
0
7
60
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
40
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% H
% Ile:
0
67
87
0
7
0
0
0
7
0
0
0
0
7
0
% I
% Lys:
34
0
0
7
0
87
74
0
7
67
0
7
0
14
7
% K
% Leu:
0
20
0
0
0
0
0
0
0
0
94
0
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
20
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
87
0
0
0
0
0
0
0
0
0
0
87
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
7
% Q
% Arg:
60
0
0
0
0
0
0
0
0
27
0
40
0
0
0
% R
% Ser:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
27
0
14
0
% T
% Val:
0
0
14
0
14
7
0
0
67
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
87
0
0
0
0
54
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _