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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHCR24
All Species:
44.85
Human Site:
Y328
Identified Species:
70.48
UniProt:
Q15392
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15392
NP_055577.1
516
60101
Y328
Y
I
P
L
R
H
Y
Y
H
R
H
T
R
S
I
Chimpanzee
Pan troglodytes
XP_001153873
516
60069
Y328
Y
I
P
L
R
H
Y
Y
H
R
H
T
R
S
I
Rhesus Macaque
Macaca mulatta
XP_001108186
590
68025
Y402
Y
I
P
L
R
H
Y
Y
H
R
H
T
R
S
I
Dog
Lupus familis
XP_546693
516
59942
Y328
Y
I
P
L
R
H
Y
Y
H
R
H
T
R
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCH6
516
60094
Y328
Y
I
P
L
R
H
Y
Y
H
R
H
T
R
S
I
Rat
Rattus norvegicus
Q5BQE6
516
60029
Y328
Y
I
P
L
R
H
Y
Y
H
R
H
T
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517895
508
58237
Y320
Y
I
P
L
R
H
Y
Y
H
R
H
T
R
S
I
Chicken
Gallus gallus
NP_001026459
516
60104
Y328
Y
I
P
S
R
H
Y
Y
H
R
H
T
R
S
I
Frog
Xenopus laevis
NP_001086259
516
59787
Y328
Y
I
P
L
R
H
Y
Y
H
R
H
T
K
S
I
Zebra Danio
Brachydanio rerio
NP_001008645
516
60258
Y328
Y
I
P
L
R
H
Y
Y
H
R
H
T
R
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17397
525
61402
Y337
Y
I
P
L
R
D
Y
Y
H
R
H
S
K
S
I
Sea Urchin
Strong. purpuratus
XP_001202234
351
40719
V178
F
W
E
I
Q
D
I
V
P
F
G
N
H
P
I
Poplar Tree
Populus trichocarpa
XP_002315056
563
65561
R335
F
V
E
Y
I
P
T
R
E
Y
Y
H
R
H
T
Maize
Zea mays
NP_001105560
562
64988
R333
F
V
E
Y
I
P
T
R
E
Y
Y
H
R
H
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39085
561
65376
R333
F
V
E
Y
I
P
T
R
E
Y
Y
H
R
H
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
86.9
96.9
N.A.
96.9
97
N.A.
77.1
78.2
78
79.4
N.A.
N.A.
N.A.
48.7
44.3
Protein Similarity:
100
100
87.2
98.8
N.A.
98.8
99
N.A.
84.1
89.9
90.3
90.6
N.A.
N.A.
N.A.
66.2
56.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
100
N.A.
N.A.
N.A.
80
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
100
N.A.
N.A.
N.A.
93.3
26.6
Percent
Protein Identity:
38.5
38.7
N.A.
38.6
N.A.
N.A.
Protein Similarity:
57.1
57.4
N.A.
56.6
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
26.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
27
0
0
0
0
0
20
0
0
0
0
0
0
% E
% Phe:
27
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
67
0
0
74
0
74
20
7
20
0
% H
% Ile:
0
74
0
7
20
0
7
0
0
0
0
0
0
0
80
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% K
% Leu:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
74
0
0
20
0
0
7
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
74
0
0
20
0
74
0
0
80
0
0
% R
% Ser:
0
0
0
7
0
0
0
0
0
0
0
7
0
74
0
% S
% Thr:
0
0
0
0
0
0
20
0
0
0
0
67
0
0
20
% T
% Val:
0
20
0
0
0
0
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
74
0
0
20
0
0
74
74
0
20
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _