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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B3
All Species:
45.15
Human Site:
Y520
Identified Species:
66.22
UniProt:
Q15393
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15393
NP_036558.3
1217
135577
Y520
D
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Chimpanzee
Pan troglodytes
XP_511081
1283
142840
Y586
D
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Rhesus Macaque
Macaca mulatta
XP_001107025
1199
133593
Y502
D
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Dog
Lupus familis
XP_536791
1217
135545
Y520
D
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q921M3
1217
135532
Y520
D
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Rat
Rattus norvegicus
XP_001077410
1216
135436
Y520
D
D
A
L
V
Q
V
Y
P
D
G
I
R
H
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506454
1217
135474
Y520
D
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Chicken
Gallus gallus
XP_001232348
1218
135585
Y520
D
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LVE8
1217
135603
Y520
E
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728546
1227
136598
Y520
D
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Honey Bee
Apis mellifera
XP_623333
1217
135272
Y520
E
D
A
L
V
Q
V
Y
P
D
G
I
R
H
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188711
1141
126889
D493
E
M
V
Y
F
E
M
D
P
T
G
Q
L
N
E
Poplar Tree
Populus trichocarpa
XP_002312063
1213
134429
H518
D
D
S
L
M
Q
I
H
P
N
G
I
R
H
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49552
1088
121161
D455
V
Q
T
L
F
C
H
D
A
V
Y
N
Q
L
V
Baker's Yeast
Sacchar. cerevisiae
Q04693
1361
153766
G595
T
I
H
T
C
L
M
G
S
H
S
I
I
Q
V
Red Bread Mold
Neurospora crassa
Q7RYR4
1209
134021
H539
E
D
G
L
I
Q
V
H
P
K
G
I
R
H
I
Conservation
Percent
Protein Identity:
100
94.8
98.1
99.9
N.A.
99.9
99.5
N.A.
99.6
99
N.A.
93.4
N.A.
75.4
80.5
N.A.
76.1
Protein Similarity:
100
94.8
98.2
100
N.A.
100
99.5
N.A.
99.9
99.6
N.A.
97.9
N.A.
86.9
90.2
N.A.
85.7
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
100
N.A.
93.3
N.A.
100
93.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
40
Percent
Protein Identity:
58.7
N.A.
N.A.
23.5
23
51
Protein Similarity:
76.1
N.A.
N.A.
42
41.5
69.5
P-Site Identity:
66.6
N.A.
N.A.
6.6
6.6
66.6
P-Site Similarity:
100
N.A.
N.A.
20
20
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
69
0
0
0
0
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
63
82
0
0
0
0
0
13
0
69
0
0
0
0
0
% D
% Glu:
25
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
7
0
0
88
0
0
0
0
% G
% His:
0
0
7
0
0
0
7
13
0
7
0
0
0
82
0
% H
% Ile:
0
7
0
0
7
0
7
0
0
0
0
88
7
0
75
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% K
% Leu:
0
0
0
88
0
7
0
0
0
0
0
0
7
7
0
% L
% Met:
0
7
0
0
7
0
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
88
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
82
0
0
0
0
0
7
7
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% R
% Ser:
0
0
7
0
0
0
0
0
7
0
7
0
0
0
0
% S
% Thr:
7
0
7
7
0
0
0
0
0
7
0
0
0
0
0
% T
% Val:
7
0
7
0
69
0
75
0
0
7
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
7
0
0
0
69
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _