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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0020 All Species: 30.91
Human Site: S227 Identified Species: 45.33
UniProt: Q15397 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15397 NP_055693.4 648 73584 S227 K K F L M Y G S K P Q I A E I
Chimpanzee Pan troglodytes XP_520461 685 77411 G264 V K K F L M Y G K P Q I A E I
Rhesus Macaque Macaca mulatta XP_001084706 576 65812 N190 Q C Y I Q Y G N E E Q R K Q A
Dog Lupus familis XP_533539 720 80879 S299 K K F L M Y G S K P Q I A E I
Cat Felis silvestris
Mouse Mus musculus Q8BKS9 647 72781 S226 K K F L M Y G S K P Q V A E I
Rat Rattus norvegicus Q562C7 647 72767 S226 K K F L M Y G S K P Q I A E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507108 729 80791 L226 H P T L D K V L E V Q P A K Q
Chicken Gallus gallus NP_001026608 611 69819 E200 E L K D S L V E L S K S K Y S
Frog Xenopus laevis NP_001086528 642 72717 S221 R K F L M Y G S K A Q V A E I
Zebra Danio Brachydanio rerio XP_695580 629 71341 S210 K K F L M Y G S K E Q V G E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61345 737 81283 A229 Q R M L K Y G A P A T K A K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09622 766 86936 T339 K K M L K N G T K E Q R D I I
Sea Urchin Strong. purpuratus XP_001197420 668 76166 S244 L K M F R Y G S K E Q R L A I
Poplar Tree Populus trichocarpa XP_002328590 655 72886 S190 T K M L D N A S K K Q L A E F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPV9 305 35024
Baker's Yeast Sacchar. cerevisiae Q04373 656 75087 S218 V K L L H Y G S R S S R Q T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 86.8 82.3 N.A. 89.5 88.5 N.A. 63.9 65.9 64.1 64.3 N.A. 26.4 N.A. 28 40.2
Protein Similarity: 100 94.1 87.8 86.1 N.A. 94.2 93.8 N.A. 72.2 79 77.6 78.8 N.A. 46.1 N.A. 47.5 59.5
P-Site Identity: 100 53.3 20 100 N.A. 93.3 100 N.A. 20 0 80 73.3 N.A. 26.6 N.A. 46.6 46.6
P-Site Similarity: 100 60 60 100 N.A. 100 100 N.A. 33.3 13.3 93.3 86.6 N.A. 60 N.A. 53.3 46.6
Percent
Protein Identity: 29.1 N.A. N.A. 20 23.4 N.A.
Protein Similarity: 49.3 N.A. N.A. 31.9 46.3 N.A.
P-Site Identity: 46.6 N.A. N.A. 0 40 N.A.
P-Site Similarity: 53.3 N.A. N.A. 0 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 7 0 13 0 0 57 7 7 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 13 0 0 0 0 0 0 0 7 0 0 % D
% Glu: 7 0 0 0 0 0 0 7 13 25 0 0 0 50 0 % E
% Phe: 0 0 38 13 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 69 7 0 0 0 0 7 0 0 % G
% His: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 25 0 7 57 % I
% Lys: 38 69 13 0 13 7 0 0 63 7 7 7 13 13 0 % K
% Leu: 7 7 7 69 7 7 0 7 7 0 0 7 7 0 7 % L
% Met: 0 0 25 0 38 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 7 32 0 7 0 0 0 % P
% Gln: 13 0 0 0 7 0 0 0 0 0 75 0 7 7 7 % Q
% Arg: 7 7 0 0 7 0 0 0 7 0 0 25 0 0 0 % R
% Ser: 0 0 0 0 7 0 0 57 0 13 7 7 0 0 7 % S
% Thr: 7 0 7 0 0 0 0 7 0 0 7 0 0 7 0 % T
% Val: 13 0 0 0 0 0 13 0 0 7 0 19 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 63 7 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _