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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLR1
All Species:
11.82
Human Site:
S690
Identified Species:
37.14
UniProt:
Q15399
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15399
NP_003254.2
786
90291
S690
I
I
T
C
I
E
K
S
Y
K
S
I
F
V
L
Chimpanzee
Pan troglodytes
B3Y613
784
89806
I685
D
F
I
P
G
K
W
I
I
D
N
I
I
D
S
Rhesus Macaque
Macaca mulatta
B3Y618
784
90053
I685
D
F
I
P
G
K
W
I
I
D
N
I
I
D
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPQ1
795
90654
S693
I
I
N
F
I
E
K
S
Y
K
S
I
F
V
L
Rat
Rattus norvegicus
Q9QX05
835
96053
K727
I
I
Q
E
G
F
H
K
S
R
K
V
I
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512973
790
88926
S690
I
I
S
C
I
E
K
S
R
K
S
I
F
V
L
Chicken
Gallus gallus
Q9DGB6
781
89077
I682
D
F
V
P
G
K
W
I
V
D
N
I
I
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124065
795
91076
S696
I
L
R
C
I
E
Q
S
R
R
C
V
F
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.8
30.9
N.A.
N.A.
73.3
22.3
N.A.
52.2
29.8
N.A.
35.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
52.4
53.4
N.A.
N.A.
84.6
42.6
N.A.
69.1
50.5
N.A.
57.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
N.A.
N.A.
86.6
20
N.A.
86.6
6.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
N.A.
N.A.
86.6
40
N.A.
93.3
20
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
38
0
0
0
0
0
0
13
0
0
0
0
% C
% Asp:
38
0
0
0
0
0
0
0
0
38
0
0
0
38
0
% D
% Glu:
0
0
0
13
0
50
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
38
0
13
0
13
0
0
0
0
0
0
50
0
0
% F
% Gly:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% H
% Ile:
63
50
25
0
50
0
0
38
25
0
0
75
50
0
0
% I
% Lys:
0
0
0
0
0
38
38
13
0
38
13
0
0
0
0
% K
% Leu:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
38
0
0
0
0
% N
% Pro:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
13
0
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
0
0
0
25
25
0
0
0
0
0
% R
% Ser:
0
0
13
0
0
0
0
50
13
0
38
0
0
0
38
% S
% Thr:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
13
0
0
0
0
0
13
0
0
25
0
63
13
% V
% Trp:
0
0
0
0
0
0
38
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _