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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSU1
All Species:
30.61
Human Site:
S268
Identified Species:
56.11
UniProt:
Q15404
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15404
NP_036557.1
277
31540
S268
N
D
K
S
K
K
I
S
R
K
P
L
A
A
K
Chimpanzee
Pan troglodytes
XP_001151338
277
31510
S268
N
D
K
S
K
K
I
S
R
K
P
L
A
A
K
Rhesus Macaque
Macaca mulatta
XP_001093095
192
21881
K185
K
S
K
K
I
S
R
K
P
L
A
A
K
N
R
Dog
Lupus familis
XP_535177
277
31507
S268
N
D
K
S
K
K
I
S
R
K
P
L
T
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q01730
277
31532
S268
N
D
K
S
K
K
I
S
R
K
P
L
A
A
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507401
462
52016
S453
N
D
K
S
K
K
I
S
R
K
P
L
A
A
R
Chicken
Gallus gallus
Q5F4C4
529
59144
P464
E
N
K
L
E
S
L
P
N
E
I
A
Y
L
K
Frog
Xenopus laevis
Q8AVI4
577
64082
A557
H
L
P
P
Q
I
V
A
G
G
P
S
F
I
I
Zebra Danio
Brachydanio rerio
XP_002666722
277
31152
S268
A
D
K
S
K
K
I
S
R
K
P
L
A
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609665
283
31831
K276
P
P
K
A
D
K
S
K
K
A
S
R
I
R
A
Honey Bee
Apis mellifera
XP_395612
283
32107
Y258
S
E
T
Y
R
Y
V
Y
N
R
H
Q
S
A
K
Nematode Worm
Caenorhab. elegans
NP_497716
268
30502
S261
R
N
K
E
K
K
V
S
R
K
G
I
Q
Q
A
Sea Urchin
Strong. purpuratus
XP_785035
276
31261
S268
N
A
K
A
K
K
I
S
R
R
E
I
Y
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
68.5
98.1
N.A.
95.6
N.A.
N.A.
53.9
21.1
21.4
90.9
N.A.
55.4
61.8
55.2
66.7
Protein Similarity:
100
99.6
68.5
99.2
N.A.
98.5
N.A.
N.A.
58.4
34
31.7
96
N.A.
74.9
76.6
73.2
83
P-Site Identity:
100
100
6.6
93.3
N.A.
100
N.A.
N.A.
93.3
13.3
6.6
93.3
N.A.
13.3
13.3
40
53.3
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
N.A.
N.A.
100
40
33.3
93.3
N.A.
26.6
53.3
60
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
16
0
0
0
8
0
8
8
16
39
54
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
8
8
0
0
0
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
8
0
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
54
0
0
0
8
16
8
8
8
% I
% Lys:
8
0
85
8
62
70
0
16
8
54
0
0
8
0
62
% K
% Leu:
0
8
0
8
0
0
8
0
0
8
0
47
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
47
16
0
0
0
0
0
0
16
0
0
0
0
8
0
% N
% Pro:
8
8
8
8
0
0
0
8
8
0
54
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
8
8
8
0
% Q
% Arg:
8
0
0
0
8
0
8
0
62
16
0
8
0
8
16
% R
% Ser:
8
8
0
47
0
16
8
62
0
0
8
8
8
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
8
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _