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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS6KA1 All Species: 32.12
Human Site: T522 Identified Species: 70.67
UniProt: Q15418 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15418 NP_001006666.1 735 82723 T522 V L H T I G K T V E Y L H S Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104305 745 83841 T530 I L Y V I S K T V D Y L H C Q
Dog Lupus familis XP_544479 744 83915 T531 V L H T I S K T V E Y L H S Q
Cat Felis silvestris
Mouse Mus musculus P18653 724 81576 T511 V L H T I S K T V E Y L H S Q
Rat Rattus norvegicus Q63531 735 82865 T522 V L Y T I S K T V E Y L H S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513942 700 79225 T486 V L F T I T K T V E Y L H A Q
Chicken Gallus gallus P18652 752 84421 T539 V L H T I C K T V E Y L H S Q
Frog Xenopus laevis P10665 733 82620 T520 V L F T V C K T V E N L H S Q
Zebra Danio Brachydanio rerio Q6PFQ0 740 83378 T524 V L Y T I T K T V D Y L H C Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3I5 1207 137026 A726 I F L Q L V M A V R H I H S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21734 784 88102 A559 I M A N L L N A V Q Y L H S Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 73 94.3 N.A. 97 97.5 N.A. 79.7 90 84.9 75.1 N.A. 24.3 N.A. 58.2 N.A.
Protein Similarity: 100 N.A. 83.4 95.5 N.A. 97.6 98.9 N.A. 86.5 93.2 90.1 85.2 N.A. 36.4 N.A. 73 N.A.
P-Site Identity: 100 N.A. 60 93.3 N.A. 93.3 86.6 N.A. 80 93.3 73.3 73.3 N.A. 20 N.A. 40 N.A.
P-Site Similarity: 100 N.A. 80 93.3 N.A. 93.3 93.3 N.A. 86.6 93.3 80 86.6 N.A. 53.3 N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 19 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 19 0 0 0 0 0 0 0 19 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 64 0 0 0 0 0 % E
% Phe: 0 10 19 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 37 0 0 0 0 0 0 0 10 0 100 0 0 % H
% Ile: 28 0 0 0 73 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 82 0 0 0 0 0 0 0 10 % K
% Leu: 0 82 10 0 19 10 0 0 0 0 0 91 0 0 0 % L
% Met: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 10 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 91 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 37 0 0 0 0 0 0 0 73 0 % S
% Thr: 0 0 0 73 0 19 0 82 0 0 0 0 0 0 0 % T
% Val: 73 0 0 10 10 10 0 0 100 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 28 0 0 0 0 0 0 0 82 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _