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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3B4 All Species: 18.18
Human Site: S242 Identified Species: 36.36
UniProt: Q15427 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15427 NP_005841.1 424 44386 S242 P G M P P P G S F P P P V P P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q7JGR2 382 43298 T248 F G F V R Y E T H E A A Q K A
Dog Lupus familis XP_540295 409 42782 S242 P G M P P P G S F P P P V P P
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q6AYL5 424 44337 S242 P G M P P P G S F P P P V P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423721 418 43905 S242 P G L P P P G S F P P P V P P
Frog Xenopus laevis P20965 633 70449 S463 A P R P P T F S T M R P A S N
Zebra Danio Brachydanio rerio NP_705947 400 41939 A242 P G M P P P G A F P P V P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393914 413 44283 M244 Q H H V M H G M V V P P P P P
Nematode Worm Caenorhab. elegans Q09442 388 40990 Y243 H A T G R P G Y Q P P P L M G
Sea Urchin Strong. purpuratus XP_784135 425 45156 M272 P G M P P P G M P P M G M P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42731 629 68654 S339 E K L K E I F S P F G T V T S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S6N6 764 82299 G598 P A G R G P Q G I P A G I P Q
Conservation
Percent
Protein Identity: 100 N.A. 24.2 95.7 N.A. N.A. 99.5 N.A. N.A. 89.8 20.5 80.6 N.A. N.A. 62.9 58.9 67.2
Protein Similarity: 100 N.A. 37 95.9 N.A. N.A. 99.7 N.A. N.A. 91.9 32.7 83.9 N.A. N.A. 69.5 66.7 72.4
P-Site Identity: 100 N.A. 6.6 100 N.A. N.A. 100 N.A. N.A. 93.3 26.6 80 N.A. N.A. 33.3 33.3 66.6
P-Site Similarity: 100 N.A. 13.3 100 N.A. N.A. 100 N.A. N.A. 100 26.6 86.6 N.A. N.A. 33.3 40 73.3
Percent
Protein Identity: N.A. N.A. N.A. 24.1 N.A. 20.4
Protein Similarity: N.A. N.A. N.A. 32.7 N.A. 31
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 26.6
P-Site Similarity: N.A. N.A. N.A. 20 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 0 0 0 0 0 9 0 0 17 9 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 9 0 9 0 0 9 0 0 0 0 0 % E
% Phe: 9 0 9 0 0 0 17 0 42 9 0 0 0 0 0 % F
% Gly: 0 59 9 9 9 0 67 9 0 0 9 17 0 0 9 % G
% His: 9 9 9 0 0 9 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 9 0 0 0 9 0 0 % I
% Lys: 0 9 0 9 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 0 17 0 0 0 0 0 0 0 0 0 9 0 0 % L
% Met: 0 0 42 0 9 0 0 17 0 9 9 0 9 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 59 9 0 59 59 67 0 0 17 67 59 59 17 67 59 % P
% Gln: 9 0 0 0 0 0 9 0 9 0 0 0 9 0 9 % Q
% Arg: 0 0 9 9 17 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 50 0 0 0 0 0 9 9 % S
% Thr: 0 0 9 0 0 9 0 9 9 0 0 9 0 9 0 % T
% Val: 0 0 0 17 0 0 0 0 9 9 0 9 42 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _