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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B4
All Species:
10.61
Human Site:
S291
Identified Species:
21.21
UniProt:
Q15427
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15427
NP_005841.1
424
44386
S291
G
H
P
G
H
G
H
S
H
P
H
P
F
P
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q7JGR2
382
43298
I278
V
G
R
A
Q
K
K
I
E
R
L
A
E
L
R
Dog
Lupus familis
XP_540295
409
42782
S291
G
H
P
G
H
G
H
S
H
P
H
P
F
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q6AYL5
424
44337
S291
G
H
P
G
H
G
H
S
H
P
H
P
F
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423721
418
43905
A280
P
G
P
P
T
G
A
A
P
T
G
G
H
P
P
Frog
Xenopus laevis
P20965
633
70449
A498
P
R
P
T
T
A
A
A
A
A
A
S
A
V
R
Zebra Danio
Brachydanio rerio
NP_705947
400
41939
P279
Q
G
G
G
G
P
P
P
G
H
P
P
F
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393914
413
44283
T292
L
P
P
M
S
M
A
T
H
P
P
L
P
P
G
Nematode Worm
Caenorhab. elegans
Q09442
388
40990
M277
V
T
P
M
P
P
P
M
P
P
T
P
G
M
T
Sea Urchin
Strong. purpuratus
XP_784135
425
45156
G308
G
M
P
H
M
G
P
G
G
M
P
P
P
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42731
629
68654
P368
G
F
V
A
F
A
T
P
E
E
A
T
E
A
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S6N6
764
82299
G627
G
R
P
Q
N
G
G
G
R
G
T
P
R
G
N
Conservation
Percent
Protein Identity:
100
N.A.
24.2
95.7
N.A.
N.A.
99.5
N.A.
N.A.
89.8
20.5
80.6
N.A.
N.A.
62.9
58.9
67.2
Protein Similarity:
100
N.A.
37
95.9
N.A.
N.A.
99.7
N.A.
N.A.
91.9
32.7
83.9
N.A.
N.A.
69.5
66.7
72.4
P-Site Identity:
100
N.A.
0
100
N.A.
N.A.
100
N.A.
N.A.
26.6
6.6
33.3
N.A.
N.A.
26.6
20
40
P-Site Similarity:
100
N.A.
0
100
N.A.
N.A.
100
N.A.
N.A.
33.3
13.3
33.3
N.A.
N.A.
33.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
32.7
N.A.
31
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
17
25
17
9
9
17
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
17
9
0
0
17
0
0
% E
% Phe:
0
9
0
0
9
0
0
0
0
0
0
0
34
0
0
% F
% Gly:
50
25
9
34
9
50
9
17
17
9
9
9
9
9
9
% G
% His:
0
25
0
9
25
0
25
0
34
9
25
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% L
% Met:
0
9
0
17
9
9
0
9
0
9
0
0
0
9
9
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
17
9
75
9
9
17
25
17
17
42
25
59
17
59
50
% P
% Gln:
9
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
9
0
0
0
0
0
9
9
0
0
9
0
17
% R
% Ser:
0
0
0
0
9
0
0
25
0
0
0
9
0
0
0
% S
% Thr:
0
9
0
9
17
0
9
9
0
9
17
9
0
0
9
% T
% Val:
17
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _