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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3B4 All Species: 10.61
Human Site: S329 Identified Species: 21.21
UniProt: Q15427 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15427 NP_005841.1 424 44386 S329 P H A G P P G S G G Q P P P R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q7JGR2 382 43298 N314 K N L D E T I N D E K L K E E
Dog Lupus familis XP_540295 409 42782 M326 P P R P P P G M P H P G P P P
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q6AYL5 424 44337 S329 P H A G P P G S G G Q P P P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423721 418 43905 S324 H H P G P P G S G G Q P P P R
Frog Xenopus laevis P20965 633 70449 A529 L N T Q P Q V A M Q Q P A V H
Zebra Danio Brachydanio rerio NP_705947 400 41939 S317 P P P G P P G S N Q P R A P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393914 413 44283 W330 A P P P T A H W G V S G P P Q
Nematode Worm Caenorhab. elegans Q09442 388 40990 M313 R T P G P P G M P G M P P P P
Sea Urchin Strong. purpuratus XP_784135 425 45156 P346 M H H G P H G P F P P P P H M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42731 629 68654 V419 P V A M Q P S V G P R M P V Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S6N6 764 82299 I677 P Q A Q K Q I I G E N L F P K
Conservation
Percent
Protein Identity: 100 N.A. 24.2 95.7 N.A. N.A. 99.5 N.A. N.A. 89.8 20.5 80.6 N.A. N.A. 62.9 58.9 67.2
Protein Similarity: 100 N.A. 37 95.9 N.A. N.A. 99.7 N.A. N.A. 91.9 32.7 83.9 N.A. N.A. 69.5 66.7 72.4
P-Site Identity: 100 N.A. 0 40 N.A. N.A. 100 N.A. N.A. 86.6 20 46.6 N.A. N.A. 20 53.3 40
P-Site Similarity: 100 N.A. 20 40 N.A. N.A. 100 N.A. N.A. 86.6 33.3 46.6 N.A. N.A. 26.6 53.3 40
Percent
Protein Identity: N.A. N.A. N.A. 24.1 N.A. 20.4
Protein Similarity: N.A. N.A. N.A. 32.7 N.A. 31
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. 26.6
P-Site Similarity: N.A. N.A. N.A. 40 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 34 0 0 9 0 9 0 0 0 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 17 0 0 0 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % F
% Gly: 0 0 0 50 0 0 59 0 50 34 0 17 0 0 0 % G
% His: 9 34 9 0 0 9 9 0 0 9 0 0 0 9 9 % H
% Ile: 0 0 0 0 0 0 17 9 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 9 0 0 0 0 0 9 0 9 0 9 % K
% Leu: 9 0 9 0 0 0 0 0 0 0 0 17 0 0 0 % L
% Met: 9 0 0 9 0 0 0 17 9 0 9 9 0 0 9 % M
% Asn: 0 17 0 0 0 0 0 9 9 0 9 0 0 0 0 % N
% Pro: 50 25 34 17 67 59 0 9 17 17 25 50 67 67 25 % P
% Gln: 0 9 0 17 9 17 0 0 0 17 34 0 0 0 9 % Q
% Arg: 9 0 9 0 0 0 0 0 0 0 9 9 0 0 25 % R
% Ser: 0 0 0 0 0 0 9 34 0 0 9 0 0 0 0 % S
% Thr: 0 9 9 0 9 9 0 0 0 0 0 0 0 0 0 % T
% Val: 0 9 0 0 0 0 9 9 0 9 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _