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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3B4 All Species: 33.94
Human Site: T138 Identified Species: 67.88
UniProt: Q15427 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15427 NP_005841.1 424 44386 T138 K I M R D P D T G N S K G Y A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q7JGR2 382 43298 S144 V V C D D N G S K G Y A Y V H
Dog Lupus familis XP_540295 409 42782 T138 K I M R D P D T G N S K G Y A
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q6AYL5 424 44337 T138 K I M R D P D T G N S K G Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423721 418 43905 T138 K I M R D P D T G N S K G Y A
Frog Xenopus laevis P20965 633 70449 G329 S A K V M M E G G R S K G F G
Zebra Danio Brachydanio rerio NP_705947 400 41939 T138 K I M R D P D T G N S K G Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393914 413 44283 T138 K I M R D P E T G N S K G F A
Nematode Worm Caenorhab. elegans Q09442 388 40990 S138 K I M R D V D S G T S K G F A
Sea Urchin Strong. purpuratus XP_784135 425 45156 S138 K I M R D V E S G N S K G Y A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42731 629 68654 S160 C K V A V D S S G Q S K G Y G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S6N6 764 82299 L421 E K K G D R K L G K S K G F G
Conservation
Percent
Protein Identity: 100 N.A. 24.2 95.7 N.A. N.A. 99.5 N.A. N.A. 89.8 20.5 80.6 N.A. N.A. 62.9 58.9 67.2
Protein Similarity: 100 N.A. 37 95.9 N.A. N.A. 99.7 N.A. N.A. 91.9 32.7 83.9 N.A. N.A. 69.5 66.7 72.4
P-Site Identity: 100 N.A. 6.6 100 N.A. N.A. 100 N.A. N.A. 100 26.6 100 N.A. N.A. 86.6 73.3 80
P-Site Similarity: 100 N.A. 20 100 N.A. N.A. 100 N.A. N.A. 100 40 100 N.A. N.A. 100 86.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 24.1 N.A. 20.4
Protein Similarity: N.A. N.A. N.A. 32.7 N.A. 31
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 0 0 0 0 9 0 0 67 % A
% Cys: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 84 9 50 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 25 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 0 % F
% Gly: 0 0 0 9 0 0 9 9 92 9 0 0 92 0 25 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 67 17 17 0 0 0 9 0 9 9 0 92 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % L
% Met: 0 0 67 0 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 59 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 67 0 9 0 0 0 9 0 0 0 0 0 % R
% Ser: 9 0 0 0 0 0 9 34 0 0 92 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 50 0 9 0 0 0 0 0 % T
% Val: 9 9 9 9 9 17 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 9 59 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _