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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3B4 All Species: 17.58
Human Site: Y396 Identified Species: 35.15
UniProt: Q15427 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15427 NP_005841.1 424 44386 Y396 P R P P P Y G Y Q R G P L P P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q7JGR2 382 43298 N362 T K A V D E M N G R V V G S K
Dog Lupus familis XP_540295 409 42782 Y381 P R P P P Y G Y Q R G P L P P
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q6AYL5 424 44337 Y396 P R P P P Y G Y Q R G P L P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423721 418 43905 Y391 P R P P P Y G Y Q R V P L P P
Frog Xenopus laevis P20965 633 70449 L584 G K I T G M L L E I D N S E L
Zebra Danio Brachydanio rerio NP_705947 400 41939 F377 P R P P P F G F Q R G P P M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393914 413 44283 S380 H P P P P P V S Q G G P P P P
Nematode Worm Caenorhab. elegans Q09442 388 40990 S357 P P P P R Y P S A G P G M Y P
Sea Urchin Strong. purpuratus XP_784135 425 45156 G404 P R G P P F G G P P H G G P H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42731 629 68654 Q498 P G G I Q H S Q Q Q N P M M Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7S6N6 764 82299 A745 Q Q P T Q Q P A E A N G E Q P
Conservation
Percent
Protein Identity: 100 N.A. 24.2 95.7 N.A. N.A. 99.5 N.A. N.A. 89.8 20.5 80.6 N.A. N.A. 62.9 58.9 67.2
Protein Similarity: 100 N.A. 37 95.9 N.A. N.A. 99.7 N.A. N.A. 91.9 32.7 83.9 N.A. N.A. 69.5 66.7 72.4
P-Site Identity: 100 N.A. 6.6 100 N.A. N.A. 100 N.A. N.A. 93.3 0 73.3 N.A. N.A. 53.3 33.3 40
P-Site Similarity: 100 N.A. 13.3 100 N.A. N.A. 100 N.A. N.A. 93.3 13.3 86.6 N.A. N.A. 53.3 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. 24.1 N.A. 20.4
Protein Similarity: N.A. N.A. N.A. 32.7 N.A. 31
P-Site Identity: N.A. N.A. N.A. 20 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 40 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 9 9 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 17 0 0 0 9 9 0 % E
% Phe: 0 0 0 0 0 17 0 9 0 0 0 0 0 0 0 % F
% Gly: 9 9 17 0 9 0 50 9 9 17 42 25 17 0 0 % G
% His: 9 0 0 0 0 9 0 0 0 0 9 0 0 0 9 % H
% Ile: 0 0 9 9 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 0 0 0 9 9 0 0 0 0 34 0 9 % L
% Met: 0 0 0 0 0 9 9 0 0 0 0 0 17 17 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 17 9 0 0 0 % N
% Pro: 67 17 67 67 59 9 17 0 9 9 9 59 17 50 67 % P
% Gln: 9 9 0 0 17 9 0 9 59 9 0 0 0 9 9 % Q
% Arg: 0 50 0 0 9 0 0 0 0 50 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 9 17 0 0 0 0 9 9 0 % S
% Thr: 9 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 9 0 0 9 0 0 0 17 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 42 0 34 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _