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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B4
All Species:
30.91
Human Site:
Y69
Identified Species:
61.82
UniProt:
Q15427
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15427
NP_005841.1
424
44386
Y69
L
S
E
E
D
A
D
Y
A
I
K
I
M
N
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q7JGR2
382
43298
W74
R
F
P
A
D
A
E
W
A
L
N
T
M
N
F
Dog
Lupus familis
XP_540295
409
42782
Y69
L
S
E
E
D
A
D
Y
A
I
K
I
M
N
M
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q6AYL5
424
44337
Y69
L
S
E
E
D
A
D
Y
A
I
K
I
M
N
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423721
418
43905
Y69
L
S
E
E
D
A
D
Y
A
I
K
I
M
N
M
Frog
Xenopus laevis
P20965
633
70449
R153
E
T
Q
E
A
A
E
R
A
I
D
K
M
N
G
Zebra Danio
Brachydanio rerio
NP_705947
400
41939
Y69
L
S
E
E
D
A
D
Y
A
I
K
I
M
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393914
413
44283
Y69
M
G
E
E
D
A
D
Y
A
I
K
I
M
N
M
Nematode Worm
Caenorhab. elegans
Q09442
388
40990
Y69
M
G
E
E
D
A
D
Y
A
I
K
I
L
N
M
Sea Urchin
Strong. purpuratus
XP_784135
425
45156
Y69
M
G
E
E
D
A
D
Y
A
I
K
V
L
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42731
629
68654
R92
T
N
P
Q
D
A
A
R
A
I
Q
E
L
N
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S6N6
764
82299
K116
N
T
T
A
D
G
E
K
A
L
E
E
L
N
Y
Conservation
Percent
Protein Identity:
100
N.A.
24.2
95.7
N.A.
N.A.
99.5
N.A.
N.A.
89.8
20.5
80.6
N.A.
N.A.
62.9
58.9
67.2
Protein Similarity:
100
N.A.
37
95.9
N.A.
N.A.
99.7
N.A.
N.A.
91.9
32.7
83.9
N.A.
N.A.
69.5
66.7
72.4
P-Site Identity:
100
N.A.
33.3
100
N.A.
N.A.
100
N.A.
N.A.
100
40
100
N.A.
N.A.
86.6
80
73.3
P-Site Similarity:
100
N.A.
53.3
100
N.A.
N.A.
100
N.A.
N.A.
100
60
100
N.A.
N.A.
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
32.7
N.A.
31
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
9
92
9
0
100
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
92
0
67
0
0
0
9
0
0
0
0
% D
% Glu:
9
0
67
75
0
0
25
0
0
0
9
17
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
25
0
0
0
9
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
84
0
59
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
0
0
67
9
0
0
0
% K
% Leu:
42
0
0
0
0
0
0
0
0
17
0
0
34
0
0
% L
% Met:
25
0
0
0
0
0
0
0
0
0
0
0
67
0
67
% M
% Asn:
9
9
0
0
0
0
0
0
0
0
9
0
0
100
0
% N
% Pro:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% R
% Ser:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
17
9
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _