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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP1R7 All Species: 29.39
Human Site: S312 Identified Species: 58.79
UniProt: Q15435 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15435 NP_002703.1 360 41564 S312 D N L L E S W S D L D E L K G
Chimpanzee Pan troglodytes XP_516206 360 41559 S312 D N L L E S W S D L D E L K G
Rhesus Macaque Macaca mulatta XP_001090766 376 43218 S328 D N L L E S W S D L D E L K G
Dog Lupus familis XP_534627 302 34479 R255 L Q S L V N L R E L Y L S H N
Cat Felis silvestris
Mouse Mus musculus Q3UM45 361 41273 S313 D N L L E S W S D L D E L K G
Rat Rattus norvegicus Q5HZV9 360 41278 S312 D N L L E S W S D L D E L K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513331 402 46176 S354 D N L I E S W S D L D E L K G
Chicken Gallus gallus XP_422655 373 42912 S301 D N L V E S W S D L D E L K G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q32PL1 345 39366 A297 D N Q I E N W A D L D E L K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650619 326 37772 L279 D D W K D I E L L K V N K A L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P45969 326 37341 S279 F S E I E Q L S K L K G L Q T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36047 338 38869 E290 Q S F E S L G E N L S A L S R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.4 80 N.A. 93.9 95.2 N.A. 77.6 75.5 N.A. 71.9 N.A. 47.2 N.A. 42.7 N.A.
Protein Similarity: 100 99.7 94.9 82.5 N.A. 97.5 98 N.A. 84.3 86 N.A. 83 N.A. 63.8 N.A. 60.2 N.A.
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. 93.3 93.3 N.A. 66.6 N.A. 6.6 N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. 100 100 N.A. 86.6 N.A. 20 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 63.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 0 0 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 75 9 0 0 9 0 0 0 67 0 67 0 0 0 0 % D
% Glu: 0 0 9 9 75 0 9 9 9 0 0 67 0 0 0 % E
% Phe: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 59 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 25 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 9 9 9 0 9 67 0 % K
% Leu: 9 0 59 50 0 9 17 9 9 92 0 9 84 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 67 0 0 0 17 0 0 9 0 0 9 0 0 17 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 9 9 0 0 9 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % R
% Ser: 0 17 9 0 9 59 0 67 0 0 9 0 9 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % T
% Val: 0 0 0 9 9 0 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 9 0 0 0 67 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _