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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R7
All Species:
32.73
Human Site:
Y258
Identified Species:
65.45
UniProt:
Q15435
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15435
NP_002703.1
360
41564
Y258
L
V
N
L
R
E
L
Y
L
S
H
N
G
I
E
Chimpanzee
Pan troglodytes
XP_516206
360
41559
Y258
L
V
N
L
R
E
L
Y
L
S
H
N
G
I
E
Rhesus Macaque
Macaca mulatta
XP_001090766
376
43218
Y274
L
V
N
L
R
E
L
Y
L
S
H
N
G
N
D
Dog
Lupus familis
XP_534627
302
34479
N203
N
R
I
R
A
I
E
N
I
D
T
L
T
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UM45
361
41273
Y259
L
V
N
L
R
E
L
Y
L
S
N
N
G
I
E
Rat
Rattus norvegicus
Q5HZV9
360
41278
Y258
L
V
N
L
R
E
L
Y
L
S
H
N
G
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513331
402
46176
Y300
L
V
N
L
R
E
L
Y
L
S
H
N
G
I
E
Chicken
Gallus gallus
XP_422655
373
42912
Y247
L
V
N
L
R
E
L
Y
L
S
N
N
G
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q32PL1
345
39366
Y243
L
V
N
L
R
E
L
Y
L
S
H
N
G
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650619
326
37772
V227
L
Y
V
S
E
N
G
V
E
T
I
E
N
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P45969
326
37341
D227
L
S
D
Q
G
L
Q
D
I
H
G
V
E
P
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36047
338
38869
T238
Y
L
S
H
N
F
I
T
K
I
E
G
L
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.4
80
N.A.
93.9
95.2
N.A.
77.6
75.5
N.A.
71.9
N.A.
47.2
N.A.
42.7
N.A.
Protein Similarity:
100
99.7
94.9
82.5
N.A.
97.5
98
N.A.
84.3
86
N.A.
83
N.A.
63.8
N.A.
60.2
N.A.
P-Site Identity:
100
100
86.6
0
N.A.
93.3
100
N.A.
100
93.3
N.A.
100
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
6.6
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
9
0
9
0
0
0
0
9
% D
% Glu:
0
0
0
0
9
67
9
0
9
0
9
9
9
9
59
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
9
0
0
0
9
9
67
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
9
50
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
9
0
17
9
9
0
0
59
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% K
% Leu:
84
9
0
67
0
9
67
0
67
0
0
9
9
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
67
0
9
9
0
9
0
0
17
67
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
9
67
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
9
0
0
0
0
0
67
0
0
0
9
9
% S
% Thr:
0
0
0
0
0
0
0
9
0
9
9
0
9
0
0
% T
% Val:
0
67
9
0
0
0
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _