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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC23A All Species: 46.97
Human Site: S27 Identified Species: 86.11
UniProt: Q15436 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15436 NP_006355.2 765 86161 S27 S W N V W P S S R L E A T R M
Chimpanzee Pan troglodytes XP_509915 748 84571 S27 S W N V W P S S R L E A T R M
Rhesus Macaque Macaca mulatta XP_001091771 765 86128 S27 S W N V W P S S R L E A T R M
Dog Lupus familis XP_850832 765 86260 S27 S W N V W P S S R L E A T R M
Cat Felis silvestris
Mouse Mus musculus Q01405 765 86143 S27 S W N V W P S S R L E A T R M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513018 765 86087 S27 S W N V W P S S R L E A T R M
Chicken Gallus gallus Q5ZK03 767 86285 S27 S W N V W P S S R L E A T R M
Frog Xenopus laevis NP_001086405 741 83183 S27 S W N V W P S S R L E A T R M
Zebra Danio Brachydanio rerio Q7SZE5 765 86062 S27 S W N V W P S S R L E A T R M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392515 768 85881 S27 T W N V W P S S R V D A T R L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780042 764 86244 S26 S W N V W P S S R L E A T R M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P15303 768 85366 S28 S T R S D A N S N V V P V G C
Red Bread Mold Neurospora crassa Q9C284 775 86260 S28 L S W N V F P S T R M E A S R
Conservation
Percent
Protein Identity: 100 96.8 99.8 97.9 N.A. 98.9 N.A. N.A. 97.5 85.5 82.6 90.9 N.A. N.A. 75 N.A. 78
Protein Similarity: 100 97.2 100 98.8 N.A. 99.8 N.A. N.A. 99.4 93 89.5 95.4 N.A. N.A. 86.9 N.A. 88.2
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 100 100 100 100 N.A. N.A. 73.3 N.A. 100
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 100 100 100 100 N.A. N.A. 100 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 50.9 56.7
Protein Similarity: N.A. N.A. N.A. N.A. 68.2 71.2
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 0 85 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 77 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 0 77 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 77 % M
% Asn: 0 0 85 8 0 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 85 8 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 85 8 0 0 0 85 8 % R
% Ser: 85 8 0 8 0 0 85 100 0 0 0 0 0 8 0 % S
% Thr: 8 8 0 0 0 0 0 0 8 0 0 0 85 0 0 % T
% Val: 0 0 0 85 8 0 0 0 0 16 8 0 8 0 0 % V
% Trp: 0 85 8 0 85 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _