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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC23A
All Species:
27.88
Human Site:
S516
Identified Species:
51.11
UniProt:
Q15436
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15436
NP_006355.2
765
86161
S516
Q
I
Q
N
I
A
A
S
F
D
Q
E
A
A
A
Chimpanzee
Pan troglodytes
XP_509915
748
84571
T508
R
N
W
A
D
A
Q
T
Q
I
Q
N
I
A
A
Rhesus Macaque
Macaca mulatta
XP_001091771
765
86128
S516
Q
I
Q
N
I
A
A
S
F
D
Q
E
A
A
A
Dog
Lupus familis
XP_850832
765
86260
S516
Q
I
Q
N
I
A
A
S
F
D
Q
E
A
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q01405
765
86143
S516
Q
I
Q
N
I
A
A
S
F
D
Q
E
A
A
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513018
765
86087
S516
Q
I
Q
N
I
A
A
S
F
D
Q
E
A
A
A
Chicken
Gallus gallus
Q5ZK03
767
86285
A518
Q
L
Q
H
I
E
A
A
F
D
Q
E
A
A
A
Frog
Xenopus laevis
NP_001086405
741
83183
A502
R
I
R
V
T
T
I
A
R
N
W
A
D
A
Q
Zebra Danio
Brachydanio rerio
Q7SZE5
765
86062
S516
Q
I
Q
S
I
A
A
S
F
D
Q
E
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392515
768
85881
G519
S
L
H
H
I
S
A
G
F
D
Q
E
A
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780042
764
86244
G517
Q
I
T
H
I
A
A
G
F
D
Q
E
A
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15303
768
85366
S522
G
T
P
A
I
A
A
S
F
D
Q
E
A
A
A
Red Bread Mold
Neurospora crassa
Q9C284
775
86260
F522
D
P
A
I
A
Q
S
F
D
Q
E
A
A
A
V
Conservation
Percent
Protein Identity:
100
96.8
99.8
97.9
N.A.
98.9
N.A.
N.A.
97.5
85.5
82.6
90.9
N.A.
N.A.
75
N.A.
78
Protein Similarity:
100
97.2
100
98.8
N.A.
99.8
N.A.
N.A.
99.4
93
89.5
95.4
N.A.
N.A.
86.9
N.A.
88.2
P-Site Identity:
100
26.6
100
100
N.A.
100
N.A.
N.A.
100
73.3
13.3
93.3
N.A.
N.A.
60
N.A.
80
P-Site Similarity:
100
40
100
100
N.A.
100
N.A.
N.A.
100
93.3
40
100
N.A.
N.A.
80
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50.9
56.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
68.2
71.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
8
70
77
16
0
0
0
16
85
100
85
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
8
77
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
8
77
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
77
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% G
% His:
0
0
8
24
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
62
0
8
77
0
8
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
39
0
0
0
0
0
8
0
8
0
0
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
62
0
54
0
0
8
8
0
8
8
85
0
0
0
8
% Q
% Arg:
16
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
8
8
54
0
0
0
0
0
0
0
% S
% Thr:
0
8
8
0
8
8
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _