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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC23A All Species: 46.06
Human Site: Y603 Identified Species: 84.44
UniProt: Q15436 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15436 NP_006355.2 765 86161 Y603 S P D E S S Y Y R H H F M R Q
Chimpanzee Pan troglodytes XP_509915 748 84571 L590 H L R R S S F L Q V F N N S P
Rhesus Macaque Macaca mulatta XP_001091771 765 86128 Y603 S P D E S S Y Y R H H F M R Q
Dog Lupus familis XP_850832 765 86260 Y603 S P D E S S Y Y R H H F M R Q
Cat Felis silvestris
Mouse Mus musculus Q01405 765 86143 Y603 S P D E S S Y Y R H H F M R Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513018 765 86087 Y603 S P D E S S Y Y R H H F M R Q
Chicken Gallus gallus Q5ZK03 767 86285 Y605 S P D E S S Y Y R H H F A R Q
Frog Xenopus laevis NP_001086405 741 83183 Y579 S P D E S S Y Y R H H F A R Q
Zebra Danio Brachydanio rerio Q7SZE5 765 86062 Y603 S P D E S T Y Y R H Q F M R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392515 768 85881 Y606 S P D E T S F Y R H M L M R E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780042 764 86244 Y604 S P D E T S F Y R H M L I R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P15303 768 85366 Y609 S P D E T A F Y R H I F T R E
Red Bread Mold Neurospora crassa Q9C284 775 86260 Y608 S P D E T A F Y R H V L N H E
Conservation
Percent
Protein Identity: 100 96.8 99.8 97.9 N.A. 98.9 N.A. N.A. 97.5 85.5 82.6 90.9 N.A. N.A. 75 N.A. 78
Protein Similarity: 100 97.2 100 98.8 N.A. 99.8 N.A. N.A. 99.4 93 89.5 95.4 N.A. N.A. 86.9 N.A. 88.2
P-Site Identity: 100 13.3 100 100 N.A. 100 N.A. N.A. 100 93.3 93.3 86.6 N.A. N.A. 66.6 N.A. 60
P-Site Similarity: 100 26.6 100 100 N.A. 100 N.A. N.A. 100 93.3 93.3 93.3 N.A. N.A. 86.6 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 50.9 56.7
Protein Similarity: N.A. N.A. N.A. N.A. 68.2 71.2
P-Site Identity: N.A. N.A. N.A. N.A. 60 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 16 0 0 0 0 0 0 16 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 93 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 93 0 0 0 0 0 0 0 0 0 0 31 % E
% Phe: 0 0 0 0 0 0 39 0 0 0 8 70 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 93 54 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 0 0 0 8 0 0 0 24 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 16 0 54 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 16 0 0 % N
% Pro: 0 93 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 62 % Q
% Arg: 0 0 8 8 0 0 0 0 93 0 0 0 0 85 0 % R
% Ser: 93 0 0 0 70 77 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 31 8 0 0 0 0 0 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 62 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _