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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC23A
All Species:
38.48
Human Site:
Y705
Identified Species:
70.56
UniProt:
Q15436
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15436
NP_006355.2
765
86161
Y705
S
R
F
P
M
P
R
Y
I
D
T
E
H
G
G
Chimpanzee
Pan troglodytes
XP_509915
748
84571
P688
F
R
H
L
L
Q
A
P
V
D
D
A
Q
E
I
Rhesus Macaque
Macaca mulatta
XP_001091771
765
86128
Y705
S
R
F
P
M
P
R
Y
I
D
T
E
H
G
G
Dog
Lupus familis
XP_850832
765
86260
Y705
S
R
F
P
M
P
R
Y
I
D
T
E
H
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q01405
765
86143
Y705
S
R
F
P
M
P
R
Y
I
D
T
E
H
G
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513018
765
86087
Y705
S
R
F
P
M
P
R
Y
I
D
T
E
H
G
G
Chicken
Gallus gallus
Q5ZK03
767
86285
Y707
T
R
F
P
M
P
R
Y
V
H
T
E
H
G
G
Frog
Xenopus laevis
NP_001086405
741
83183
Y681
S
R
F
P
M
P
R
Y
I
N
T
E
H
G
G
Zebra Danio
Brachydanio rerio
Q7SZE5
765
86062
Y705
T
R
F
P
M
P
R
Y
I
D
T
E
H
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392515
768
85881
Y708
E
R
F
P
A
P
R
Y
I
D
T
E
Q
G
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780042
764
86244
Y705
N
R
F
P
M
P
R
Y
I
V
C
E
E
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15303
768
85366
L708
L
L
V
D
R
F
P
L
P
R
F
I
D
T
E
Red Bread Mold
Neurospora crassa
Q9C284
775
86260
F711
D
R
F
P
L
P
R
F
I
V
C
D
Q
G
G
Conservation
Percent
Protein Identity:
100
96.8
99.8
97.9
N.A.
98.9
N.A.
N.A.
97.5
85.5
82.6
90.9
N.A.
N.A.
75
N.A.
78
Protein Similarity:
100
97.2
100
98.8
N.A.
99.8
N.A.
N.A.
99.4
93
89.5
95.4
N.A.
N.A.
86.9
N.A.
88.2
P-Site Identity:
100
13.3
100
100
N.A.
100
N.A.
N.A.
100
80
93.3
93.3
N.A.
N.A.
80
N.A.
66.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
N.A.
N.A.
100
93.3
100
100
N.A.
N.A.
80
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50.9
56.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
68.2
71.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
62
8
8
8
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
77
8
8
8
% E
% Phe:
8
0
85
0
0
8
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
85
77
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
0
62
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
77
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
8
8
0
8
16
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
85
0
85
8
8
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
24
0
0
% Q
% Arg:
0
93
0
0
8
0
85
0
0
8
0
0
0
0
0
% R
% Ser:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
16
0
0
0
0
0
0
0
0
0
70
0
0
8
0
% T
% Val:
0
0
8
0
0
0
0
0
16
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _