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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3A1
All Species:
34.85
Human Site:
S359
Identified Species:
69.7
UniProt:
Q15459
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15459
NP_001005409.1
793
88886
S359
V
Q
D
M
D
E
G
S
D
D
E
E
E
G
Q
Chimpanzee
Pan troglodytes
XP_515067
793
88845
S359
V
Q
D
M
D
E
G
S
D
D
E
E
E
G
Q
Rhesus Macaque
Macaca mulatta
XP_001109090
793
88798
S359
V
Q
D
M
D
E
G
S
D
D
E
E
E
G
Q
Dog
Lupus familis
XP_534733
793
88764
S359
V
Q
D
M
D
E
G
S
D
D
E
E
E
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Z5
791
88526
S357
V
Q
D
M
D
E
G
S
D
D
E
E
E
G
Q
Rat
Rattus norvegicus
NP_001100705
791
88569
S357
V
Q
D
M
D
E
G
S
D
D
E
E
E
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026643
791
88489
S356
V
Q
D
M
D
E
G
S
D
D
E
D
E
S
Q
Frog
Xenopus laevis
NP_001085709
802
90334
S353
V
Q
D
M
D
E
G
S
D
D
E
E
Y
T
S
Zebra Danio
Brachydanio rerio
NP_956388
780
87898
S346
L
Q
D
M
D
E
G
S
D
E
D
D
D
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650583
784
88057
V348
V
G
I
Q
M
K
N
V
S
S
Y
G
Q
P
T
Honey Bee
Apis mellifera
XP_393373
766
86238
E344
M
E
E
D
S
S
D
E
D
D
V
S
P
P
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXF1
785
87576
E386
I
E
N
V
H
D
E
E
A
P
M
R
I
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.6
98.6
N.A.
98.1
98.1
N.A.
N.A.
92.4
86.2
84.1
N.A.
52.4
58.1
N.A.
N.A.
Protein Similarity:
100
99.7
99.7
99.2
N.A.
98.3
98.4
N.A.
N.A.
95.4
92.3
91
N.A.
68
72.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
80
60
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
80
93.3
N.A.
20
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
75
9
75
9
9
0
84
75
9
17
9
0
0
% D
% Glu:
0
17
9
0
0
75
9
17
0
9
67
59
59
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
75
0
0
0
0
9
0
59
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
9
0
0
75
9
0
0
0
0
0
9
0
0
0
9
% M
% Asn:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
9
17
0
% P
% Gln:
0
75
0
9
0
0
0
0
0
0
0
0
9
0
59
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
0
0
0
9
9
0
75
9
9
0
9
0
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% T
% Val:
75
0
0
9
0
0
0
9
0
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _