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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3A1 All Species: 36.36
Human Site: Y193 Identified Species: 72.73
UniProt: Q15459 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15459 NP_001005409.1 793 88886 Y193 M Q K E Q R N Y Q F D F L R P
Chimpanzee Pan troglodytes XP_515067 793 88845 Y193 M Q K E Q R N Y Q F D F L R P
Rhesus Macaque Macaca mulatta XP_001109090 793 88798 Y193 M Q K E Q R N Y Q F D F L R P
Dog Lupus familis XP_534733 793 88764 Y193 M Q K E Q R N Y Q F D F L R P
Cat Felis silvestris
Mouse Mus musculus Q8K4Z5 791 88526 Y193 M Q K E Q R N Y Q F D F L R P
Rat Rattus norvegicus NP_001100705 791 88569 Y193 M Q K E Q R N Y Q F D F L R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026643 791 88489 Y190 M Q K E Q R N Y Q F D F L R P
Frog Xenopus laevis NP_001085709 802 90334 Y186 M Q K E Q R N Y Q F D F L R P
Zebra Danio Brachydanio rerio NP_956388 780 87898 Y179 M Q K E Q R N Y Q F D F L R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650583 784 88057 F178 M S R E Q R N F Q F D F L R P
Honey Bee Apis mellifera XP_393373 766 86238 F178 M N R E Q R N F Q F D F L R P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXF1 785 87576 P220 S N R E N N N P Q F H F M K P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.6 98.6 N.A. 98.1 98.1 N.A. N.A. 92.4 86.2 84.1 N.A. 52.4 58.1 N.A. N.A.
Protein Similarity: 100 99.7 99.7 99.2 N.A. 98.3 98.4 N.A. N.A. 95.4 92.3 91 N.A. 68 72.5 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 80 80 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 93.3 93.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 37 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 55.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 92 0 0 0 0 % D
% Glu: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 17 0 100 0 100 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 75 0 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 92 0 0 % L
% Met: 92 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 17 0 0 9 9 100 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 100 % P
% Gln: 0 75 0 0 92 0 0 0 100 0 0 0 0 0 0 % Q
% Arg: 0 0 25 0 0 92 0 0 0 0 0 0 0 92 0 % R
% Ser: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _