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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHB
All Species:
9.09
Human Site:
S365
Identified Species:
28.57
UniProt:
Q15464
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15464
NP_003019.2
509
55042
S365
E
K
R
Q
S
S
P
S
P
S
R
D
R
R
R
Chimpanzee
Pan troglodytes
XP_001146974
435
47987
P306
P
R
L
S
A
G
N
P
K
S
A
K
P
L
S
Rhesus Macaque
Macaca mulatta
XP_001111408
422
46812
N292
P
P
R
L
S
A
G
N
P
K
S
A
K
P
L
Dog
Lupus familis
XP_538741
623
67323
S479
E
K
R
Q
S
S
P
S
P
S
R
D
R
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PD21
503
54689
S361
R
Q
S
S
P
S
P
S
R
D
R
R
R
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511560
269
30754
G140
Q
L
R
A
P
G
G
G
F
K
P
I
K
H
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q8UUU2
722
83110
S535
E
K
L
K
S
R
I
S
E
I
V
D
S
K
R
Zebra Danio
Brachydanio rerio
NP_001038542
391
44295
G262
S
R
A
P
P
T
T
G
S
M
K
L
R
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.6
32.8
78.9
N.A.
92.9
N.A.
N.A.
47.1
N.A.
20.3
41.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
43.6
45.5
79.6
N.A.
95.4
N.A.
N.A.
50.6
N.A.
34.3
52
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
20
100
N.A.
33.3
N.A.
N.A.
6.6
N.A.
40
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
40
100
N.A.
46.6
N.A.
N.A.
20
N.A.
53.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
13
13
13
0
0
0
0
13
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
13
0
38
0
0
0
% D
% Glu:
38
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
25
25
25
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
0
0
13
0
0
13
0
13
0
0
0
% I
% Lys:
0
38
0
13
0
0
0
0
13
25
13
13
25
25
0
% K
% Leu:
0
13
25
13
0
0
0
0
0
0
0
13
0
13
25
% L
% Met:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
13
0
0
0
0
0
0
0
% N
% Pro:
25
13
0
13
38
0
38
13
38
0
13
0
13
13
13
% P
% Gln:
13
13
0
25
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
13
25
50
0
0
13
0
0
13
0
38
13
50
25
38
% R
% Ser:
13
0
13
25
50
38
0
50
13
38
13
0
13
0
13
% S
% Thr:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _