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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SKIV2L All Species: 16.67
Human Site: S142 Identified Species: 33.33
UniProt: Q15477 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15477 NP_008860.4 1246 137799 S142 R R P P G P A S Q S L W G N P
Chimpanzee Pan troglodytes XP_001160927 1246 137607 S142 R R P P G P A S Q S L W G N P
Rhesus Macaque Macaca mulatta XP_001106475 1196 132165 R136 T T S L S L R R P P G P A S Q
Dog Lupus familis XP_538841 1246 137947 S142 R R P P G P I S Q S L W G N P
Cat Felis silvestris
Mouse Mus musculus Q9CZU3 1040 117618 L50 G K R L D T K L Q S E S A S G
Rat Rattus norvegicus NP_998724 1241 136937 S142 R R P P G P A S Q S L W G N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038366 1230 137394 S149 Q R Q P G P P S E S L R G S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524465 1197 135749 G127 D V S N F Q F G D K L L T V P
Honey Bee Apis mellifera XP_397131 1212 138972 E133 F W P G G F D E P E M I V D S
Nematode Worm Caenorhab. elegans Q23223 1026 116352 K36 E K L D S A K K R Q A R E D M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190280 1347 151165 K155 P R M V G P P K D F L R G S V
Baker's Yeast Sacchar. cerevisiae P35207 1287 146040 Q145 T R S I N H N Q N S V R G S T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 92.6 94.5 N.A. 32.7 93.2 N.A. N.A. N.A. N.A. 60.2 N.A. 42.6 40.8 32.1 N.A.
Protein Similarity: 100 99.6 93.6 96.8 N.A. 48.6 96.5 N.A. N.A. N.A. N.A. 74.3 N.A. 58.3 59.5 49.1 N.A.
P-Site Identity: 100 100 0 93.3 N.A. 13.3 100 N.A. N.A. N.A. N.A. 53.3 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 100 6.6 93.3 N.A. 26.6 100 N.A. N.A. N.A. N.A. 73.3 N.A. 13.3 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 40.1 37.7 N.A.
Protein Similarity: N.A. N.A. N.A. 55.9 54 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 25 0 0 0 9 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 9 0 9 0 17 0 0 0 0 17 0 % D
% Glu: 9 0 0 0 0 0 0 9 9 9 9 0 9 0 0 % E
% Phe: 9 0 0 0 9 9 9 0 0 9 0 0 0 0 0 % F
% Gly: 9 0 0 9 59 0 0 9 0 0 9 0 59 0 9 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 9 0 0 0 0 9 0 0 0 % I
% Lys: 0 17 0 0 0 0 17 17 0 9 0 0 0 0 0 % K
% Leu: 0 0 9 17 0 9 0 9 0 0 59 9 0 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 9 % M
% Asn: 0 0 0 9 9 0 9 0 9 0 0 0 0 34 9 % N
% Pro: 9 0 42 42 0 50 17 0 17 9 0 9 0 0 42 % P
% Gln: 9 0 9 0 0 9 0 9 42 9 0 0 0 0 9 % Q
% Arg: 34 59 9 0 0 0 9 9 9 0 0 34 0 0 0 % R
% Ser: 0 0 25 0 17 0 0 42 0 59 0 9 0 42 9 % S
% Thr: 17 9 0 0 0 9 0 0 0 0 0 0 9 0 9 % T
% Val: 0 9 0 9 0 0 0 0 0 0 9 0 9 9 9 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 34 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _