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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKIV2L
All Species:
13.64
Human Site:
S270
Identified Species:
27.27
UniProt:
Q15477
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15477
NP_008860.4
1246
137799
S270
K
E
A
S
T
A
V
S
T
P
E
A
P
E
P
Chimpanzee
Pan troglodytes
XP_001160927
1246
137607
S270
K
E
A
S
T
A
V
S
T
P
E
A
P
E
P
Rhesus Macaque
Macaca mulatta
XP_001106475
1196
132165
P246
R
D
A
V
S
A
S
P
C
S
T
P
L
A
R
Dog
Lupus familis
XP_538841
1246
137947
S270
K
E
T
S
T
A
I
S
P
P
E
P
P
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZU3
1040
117618
H160
Q
S
V
L
V
S
A
H
T
S
A
G
K
T
V
Rat
Rattus norvegicus
NP_998724
1241
136937
S264
K
E
A
S
T
V
V
S
T
L
E
P
L
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038366
1230
137394
K278
G
S
L
T
E
Q
K
K
K
N
L
E
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524465
1197
135749
E237
N
F
K
S
D
W
A
E
M
V
D
I
S
Q
P
Honey Bee
Apis mellifera
XP_397131
1212
138972
E248
E
T
I
T
E
W
A
E
Q
L
D
V
S
V
P
Nematode Worm
Caenorhab. elegans
Q23223
1026
116352
S146
N
N
Q
S
V
L
V
S
A
H
T
S
A
G
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190280
1347
151165
M315
S
S
A
K
T
A
I
M
S
E
E
A
V
T
G
Baker's Yeast
Sacchar. cerevisiae
P35207
1287
146040
T289
I
G
I
D
F
G
R
T
K
P
V
S
K
S
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
92.6
94.5
N.A.
32.7
93.2
N.A.
N.A.
N.A.
N.A.
60.2
N.A.
42.6
40.8
32.1
N.A.
Protein Similarity:
100
99.6
93.6
96.8
N.A.
48.6
96.5
N.A.
N.A.
N.A.
N.A.
74.3
N.A.
58.3
59.5
49.1
N.A.
P-Site Identity:
100
100
13.3
66.6
N.A.
6.6
66.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
13.3
6.6
20
N.A.
P-Site Similarity:
100
100
33.3
80
N.A.
20
73.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
26.6
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.1
37.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
54
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
0
0
42
25
0
9
0
9
25
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
9
0
0
0
0
0
17
0
0
0
0
% D
% Glu:
9
34
0
0
17
0
0
17
0
9
42
9
9
25
0
% E
% Phe:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
9
0
0
0
0
0
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% H
% Ile:
9
0
17
0
0
0
17
0
0
0
0
9
0
0
0
% I
% Lys:
34
0
9
9
0
0
9
9
17
0
0
0
17
17
17
% K
% Leu:
0
0
9
9
0
9
0
0
0
17
9
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% M
% Asn:
17
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
9
34
0
25
25
0
50
% P
% Gln:
9
0
9
0
0
9
0
0
9
0
0
0
0
9
0
% Q
% Arg:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% R
% Ser:
9
25
0
50
9
9
9
42
9
17
0
17
17
9
0
% S
% Thr:
0
9
9
17
42
0
0
9
34
0
17
0
0
17
0
% T
% Val:
0
0
9
9
17
9
34
0
0
9
9
9
9
9
17
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _