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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SKIV2L All Species: 26.36
Human Site: S405 Identified Species: 52.73
UniProt: Q15477 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15477 NP_008860.4 1246 137799 S405 M T T E I L R S M L Y S G S D
Chimpanzee Pan troglodytes XP_001160927 1246 137607 S405 M T T E I L R S M L Y S G S D
Rhesus Macaque Macaca mulatta XP_001106475 1196 132165 Q368 P I K A L S N Q K F R D F R N
Dog Lupus familis XP_538841 1246 137947 S405 M T T E I L R S M L Y S G S D
Cat Felis silvestris
Mouse Mus musculus Q9CZU3 1040 117618 L280 D N V H Y V F L S A T I P N A
Rat Rattus norvegicus NP_998724 1241 136937 S399 M T T E I L R S M L Y S G S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038366 1230 137394 S413 M T T E I L R S M L Y N G S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524465 1197 135749 S357 M T T E I L R S M L Y C G S D
Honey Bee Apis mellifera XP_397131 1212 138972 S368 I T T E I L Q S M L Y C A S E
Nematode Worm Caenorhab. elegans Q23223 1026 116352 A266 M S K N I K Q A F L S A T I P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190280 1347 151165 M455 T T E I L R S M L Y R G A D I
Baker's Yeast Sacchar. cerevisiae P35207 1287 146040 L424 L I M T T E I L R S M L Y R G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 92.6 94.5 N.A. 32.7 93.2 N.A. N.A. N.A. N.A. 60.2 N.A. 42.6 40.8 32.1 N.A.
Protein Similarity: 100 99.6 93.6 96.8 N.A. 48.6 96.5 N.A. N.A. N.A. N.A. 74.3 N.A. 58.3 59.5 49.1 N.A.
P-Site Identity: 100 100 0 100 N.A. 0 100 N.A. N.A. N.A. N.A. 86.6 N.A. 93.3 66.6 20 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 13.3 100 N.A. N.A. N.A. N.A. 100 N.A. 93.3 86.6 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 40.1 37.7 N.A.
Protein Similarity: N.A. N.A. N.A. 55.9 54 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 9 0 9 0 9 17 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 0 9 0 9 42 % D
% Glu: 0 0 9 59 0 9 0 0 0 0 0 0 0 0 17 % E
% Phe: 0 0 0 0 0 0 9 0 9 9 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 9 50 0 9 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 17 0 9 67 0 9 0 0 0 0 9 0 9 9 % I
% Lys: 0 0 17 0 0 9 0 0 9 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 17 59 0 17 9 67 0 9 0 0 0 % L
% Met: 59 0 9 0 0 0 0 9 59 0 9 0 0 0 0 % M
% Asn: 0 9 0 9 0 0 9 0 0 0 0 9 0 9 9 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % P
% Gln: 0 0 0 0 0 0 17 9 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 50 0 9 0 17 0 0 17 0 % R
% Ser: 0 9 0 0 0 9 9 59 9 9 9 34 0 59 0 % S
% Thr: 9 67 59 9 9 0 0 0 0 0 9 0 9 0 0 % T
% Val: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 9 59 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _