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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKIV2L
All Species:
17.88
Human Site:
S945
Identified Species:
35.76
UniProt:
Q15477
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15477
NP_008860.4
1246
137799
S945
E
K
I
L
E
D
F
S
K
R
Q
Q
P
K
F
Chimpanzee
Pan troglodytes
XP_001160927
1246
137607
S945
E
K
I
L
E
D
F
S
K
R
Q
Q
P
K
F
Rhesus Macaque
Macaca mulatta
XP_001106475
1196
132165
S895
E
K
I
L
E
D
F
S
K
R
Q
Q
P
K
F
Dog
Lupus familis
XP_538841
1246
137947
S945
E
K
I
L
E
D
F
S
K
R
Q
Q
P
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZU3
1040
117618
D780
P
L
L
D
P
I
D
D
M
G
I
Q
D
Q
G
Rat
Rattus norvegicus
NP_998724
1241
136937
S940
E
K
I
S
E
D
F
S
K
R
Q
Q
P
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038366
1230
137394
N934
E
R
I
I
D
N
Y
N
K
R
L
Q
P
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524465
1197
135749
E894
D
A
I
I
R
N
W
E
Q
R
Q
L
E
R
F
Honey Bee
Apis mellifera
XP_397131
1212
138972
E916
N
L
V
L
A
N
W
E
K
R
Q
I
P
R
F
Nematode Worm
Caenorhab. elegans
Q23223
1026
116352
Q766
I
P
L
L
D
P
I
Q
D
M
E
I
K
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190280
1347
151165
D1039
K
E
F
L
C
I
C
D
S
K
I
K
I
D
Q
Baker's Yeast
Sacchar. cerevisiae
P35207
1287
146040
K997
A
P
L
G
K
V
I
K
K
D
V
A
A
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
92.6
94.5
N.A.
32.7
93.2
N.A.
N.A.
N.A.
N.A.
60.2
N.A.
42.6
40.8
32.1
N.A.
Protein Similarity:
100
99.6
93.6
96.8
N.A.
48.6
96.5
N.A.
N.A.
N.A.
N.A.
74.3
N.A.
58.3
59.5
49.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
93.3
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
26.6
40
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
93.3
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
66.6
66.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.1
37.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
54
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
0
0
0
0
0
9
9
0
0
% A
% Cys:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
17
42
9
17
9
9
0
0
9
9
0
% D
% Glu:
50
9
0
0
42
0
0
17
0
0
9
0
9
0
0
% E
% Phe:
0
0
9
0
0
0
42
0
0
0
0
0
0
0
67
% F
% Gly:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
59
17
0
17
17
0
0
0
17
17
9
0
0
% I
% Lys:
9
42
0
0
9
0
0
9
67
9
0
9
9
42
0
% K
% Leu:
0
17
25
59
0
0
0
0
0
0
9
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
25
0
9
0
0
0
0
0
0
9
% N
% Pro:
9
17
0
0
9
9
0
0
0
0
0
0
59
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
9
0
59
59
0
9
9
% Q
% Arg:
0
9
0
0
9
0
0
0
0
67
0
0
0
25
0
% R
% Ser:
0
0
0
9
0
0
0
42
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
9
0
0
9
0
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _