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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED22
All Species:
13.33
Human Site:
T107
Identified Species:
22.56
UniProt:
Q15528
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15528
NP_598395.1
200
22221
T107
Q
R
N
Q
Q
L
R
T
L
Q
E
E
C
D
R
Chimpanzee
Pan troglodytes
XP_528453
200
22182
A107
Q
R
N
Q
Q
L
R
A
L
Q
E
E
C
D
R
Rhesus Macaque
Macaca mulatta
XP_001101391
200
22172
A107
Q
R
N
Q
Q
L
R
A
L
Q
E
E
C
D
R
Dog
Lupus familis
XP_537799
140
16415
V48
K
I
E
D
E
T
Q
V
S
R
A
T
Q
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q62276
200
22263
A107
Q
R
N
Q
Q
L
R
A
L
Q
E
E
C
D
R
Rat
Rattus norvegicus
A0JPN6
200
22293
A107
Q
R
N
Q
Q
L
R
A
L
Q
E
E
C
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510904
140
16290
V48
K
I
E
E
E
T
Q
V
S
R
A
T
Q
G
E
Chicken
Gallus gallus
Q800L3
203
23030
S107
Q
R
N
Q
Q
L
R
S
L
Q
E
E
C
D
K
Frog
Xenopus laevis
Q6GQ95
201
22927
T107
Q
R
N
Q
Q
L
R
T
L
R
E
E
C
D
K
Zebra Danio
Brachydanio rerio
A5WUL3
198
22663
R106
S
L
R
N
Q
Q
L
R
T
L
Q
E
E
C
D
Tiger Blowfish
Takifugu rubipres
O57595
200
22905
S107
L
Q
N
Q
Q
L
R
S
L
Q
E
E
C
D
K
Fruit Fly
Dros. melanogaster
Q9V439
143
16575
I51
R
R
E
S
H
S
Q
I
S
K
T
T
Q
C
E
Honey Bee
Apis mellifera
XP_394449
140
16081
L48
K
G
E
S
D
S
Q
L
S
R
M
T
Q
C
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788097
146
16738
Q53
A
K
V
E
D
E
T
Q
V
A
R
Q
A
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99.5
68
N.A.
95
95.5
N.A.
63.5
80.7
74.1
70.5
71
45
49.5
N.A.
46
Protein Similarity:
100
99
99.5
68.5
N.A.
95.5
96
N.A.
67.5
86.6
82.5
79
77.5
57.5
60.5
N.A.
57
P-Site Identity:
100
93.3
93.3
0
N.A.
93.3
93.3
N.A.
0
86.6
86.6
13.3
73.3
6.6
0
N.A.
0
P-Site Similarity:
100
93.3
93.3
26.6
N.A.
93.3
93.3
N.A.
33.3
100
100
20
93.3
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
29
0
8
15
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
58
22
0
% C
% Asp:
0
0
0
8
15
0
0
0
0
0
0
0
0
58
8
% D
% Glu:
0
0
29
15
15
8
0
0
0
0
58
65
8
0
29
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
15
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
22
8
0
0
0
0
0
0
0
8
0
0
0
0
22
% K
% Leu:
8
8
0
0
0
58
8
8
58
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
58
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
50
8
0
58
65
8
29
8
0
50
8
8
29
8
0
% Q
% Arg:
8
58
8
0
0
0
58
8
0
29
8
0
0
0
36
% R
% Ser:
8
0
0
15
0
15
0
15
29
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
15
8
15
8
0
8
29
0
0
0
% T
% Val:
0
0
8
0
0
0
0
15
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _