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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SS18 All Species: 22.27
Human Site: Y416 Identified Species: 49
UniProt: Q15532 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15532 NP_001007560.1 418 45929 Y416 D Q G Q Y G N Y Q Q _ _ _ _ _
Chimpanzee Pan troglodytes XP_512069 479 52522 Y477 D Q G Q Y G N Y Q Q _ _ _ _ _
Rhesus Macaque Macaca mulatta XP_001098462 464 50754 Y462 D Q G Q Y G N Y Q Q _ _ _ _ _
Dog Lupus familis XP_543083 678 72149 C569 W L W A V G R C V L R F Y S G
Cat Felis silvestris
Mouse Mus musculus Q62280 418 45873 Y416 D Q G Q Y G N Y Q Q _ _ _ _ _
Rat Rattus norvegicus NP_001094370 418 45680 Y416 D Q G Q Y G N Y Q Q _ _ _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505410 440 48393 A432 D Q V K V S P A E A F G A I V
Chicken Gallus gallus NP_001072947 352 38384
Frog Xenopus laevis NP_001080622 386 42673 Y384 D Q A Q Y G N Y Q Q _ _ _ _ _
Zebra Danio Brachydanio rerio NP_956038 368 40152
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624990 608 63687 P579 P Q Y P P R P P G G H M P P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87 89.4 30.2 N.A. 95.9 94.9 N.A. 76.1 82.3 78.2 68.9 N.A. N.A. 34 N.A. N.A.
Protein Similarity: 100 87.2 89.8 39.3 N.A. 98.3 98.3 N.A. 81.8 83.2 83.2 74.8 N.A. N.A. 40.4 N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 13.3 0 90 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. 40 0 90 0 N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 10 0 10 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % F
% Gly: 0 0 46 0 0 64 0 0 10 10 0 10 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 55 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 10 10 0 19 10 0 0 0 0 10 10 10 % P
% Gln: 0 73 0 55 0 0 0 0 55 55 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 10 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 19 0 0 0 10 0 0 0 0 0 10 % V
% Trp: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 55 0 0 55 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 55 55 55 55 55 % _