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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MMD All Species: 22.73
Human Site: S126 Identified Species: 55.56
UniProt: Q15546 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15546 NP_036461.2 238 27667 S126 R E L G P L A S H M R W F I W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088388 122 14393 K13 L L D F Q K T K Y A R F M N H
Dog Lupus familis XP_537684 238 27657 S126 R E L G P L A S H M R W F I W
Cat Felis silvestris
Mouse Mus musculus Q9CQY7 238 27658 S126 R E L G P L A S H M R W F I W
Rat Rattus norvegicus Q719N3 238 27630 S126 R E L G P L A S H M R W F I W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521664 248 28545 S136 R E L G P L A S H M R W F I W
Chicken Gallus gallus NP_001025875 239 27770 S127 R E L G P L A S H M R W F I W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032496 239 27786 A126 R E L G P L A A H M R W F V W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572382 313 35229 G184 M I Y V F I A G S Y F P W L T
Honey Bee Apis mellifera XP_395667 234 26915 L119 H F P D D E I L F T M R Y A I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 33.6 99.1 N.A. 99.1 98.7 N.A. 86.6 89.9 N.A. 79 N.A. 35.1 43.2 N.A. N.A.
Protein Similarity: 100 N.A. 40.7 99.5 N.A. 100 100 N.A. 92.3 95.4 N.A. 87 N.A. 46 60.9 N.A. N.A.
P-Site Identity: 100 N.A. 6.6 100 N.A. 100 100 N.A. 100 100 N.A. 86.6 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 N.A. 20 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 26.6 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 80 10 0 10 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 70 0 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 10 10 0 0 0 10 0 10 10 70 0 0 % F
% Gly: 0 0 0 70 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 70 0 0 0 0 0 10 % H
% Ile: 0 10 0 0 0 10 10 0 0 0 0 0 0 60 10 % I
% Lys: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % K
% Leu: 10 10 70 0 0 70 0 10 0 0 0 0 0 10 0 % L
% Met: 10 0 0 0 0 0 0 0 0 70 10 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 10 0 70 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 70 0 0 0 0 0 0 0 0 0 80 10 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 60 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 70 10 0 70 % W
% Tyr: 0 0 10 0 0 0 0 0 10 10 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _