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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFBI
All Species:
29.7
Human Site:
Y448
Identified Species:
81.67
UniProt:
Q15582
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15582
NP_000349.1
683
74681
Y448
K
D
Q
L
A
S
K
Y
L
Y
H
G
Q
T
L
Chimpanzee
Pan troglodytes
XP_001169234
679
74065
Y448
K
D
Q
L
A
S
K
Y
L
Y
H
G
Q
T
L
Rhesus Macaque
Macaca mulatta
XP_001111447
683
74652
Y448
K
D
Q
L
A
S
K
Y
L
Y
H
G
Q
T
L
Dog
Lupus familis
XP_538640
661
72022
Y426
K
D
Q
L
A
S
K
Y
L
Y
H
G
Q
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P82198
683
74579
Y448
K
E
Q
L
A
S
K
Y
L
Y
S
G
Q
T
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507257
605
66035
L377
H
L
Y
H
G
Q
T
L
D
T
L
G
G
K
K
Chicken
Gallus gallus
NP_990367
680
74402
Y440
K
D
Q
L
S
S
K
Y
L
Y
H
G
Q
K
L
Frog
Xenopus laevis
NP_001088707
676
73920
Y443
K
E
T
L
S
S
K
Y
L
Y
H
G
Q
A
L
Zebra Danio
Brachydanio rerio
NP_878282
677
74172
S441
K
E
K
F
S
S
K
S
L
Y
H
G
Q
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
98.5
88.2
N.A.
90.6
N.A.
N.A.
76.5
78
72.7
61.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
99.7
93.2
N.A.
95.4
N.A.
N.A.
84.4
89.5
85.6
76.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
6.6
86.6
73.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
6.6
93.3
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
56
0
0
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
56
0
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
34
0
0
0
0
0
0
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
0
0
0
0
0
0
100
12
0
0
% G
% His:
12
0
0
12
0
0
0
0
0
0
78
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
89
0
12
0
0
0
89
0
0
0
0
0
0
23
12
% K
% Leu:
0
12
0
78
0
0
0
12
89
0
12
0
0
0
89
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
67
0
0
12
0
0
0
0
0
0
89
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
34
89
0
12
0
0
12
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
12
0
0
12
0
0
0
56
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
78
0
89
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _