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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TGFBI All Species: 21.21
Human Site: Y488 Identified Species: 58.33
UniProt: Q15582 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15582 NP_000349.1 683 74681 Y488 A H D K R G R Y G T L F T M D
Chimpanzee Pan troglodytes XP_001169234 679 74065 Y488 A H D K R G R Y G T L F T M D
Rhesus Macaque Macaca mulatta XP_001111447 683 74652 Y488 A H D K R G R Y G T L F T M D
Dog Lupus familis XP_538640 661 72022 Y466 A H D K R G R Y G T L F T M D
Cat Felis silvestris
Mouse Mus musculus P82198 683 74579 F488 A H D K R G R F G T L F T M D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507257 605 66035 D417 F G T L F T V D R M L S P P M
Chicken Gallus gallus NP_990367 680 74402 F480 A H D K R G R F G T L F S V D
Frog Xenopus laevis NP_001088707 676 73920 Y483 A H D K K G R Y G T L F I V D
Zebra Danio Brachydanio rerio NP_878282 677 74172 Y481 A H D K N G R Y A N M F L V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 98.5 88.2 N.A. 90.6 N.A. N.A. 76.5 78 72.7 61.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.6 99.7 93.2 N.A. 95.4 N.A. N.A. 84.4 89.5 85.6 76.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 6.6 80 80 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 100 93.3 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 89 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 89 0 0 0 0 12 0 0 0 0 0 0 89 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 12 0 0 0 12 0 0 23 0 0 0 89 0 0 0 % F
% Gly: 0 12 0 0 0 89 0 0 78 0 0 0 0 0 0 % G
% His: 0 89 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % I
% Lys: 0 0 0 89 12 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 12 0 0 0 0 0 0 89 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 12 12 0 0 56 12 % M
% Asn: 0 0 0 0 12 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 12 12 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 67 0 89 0 12 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 12 12 0 0 % S
% Thr: 0 0 12 0 0 12 0 0 0 78 0 0 56 0 0 % T
% Val: 0 0 0 0 0 0 12 0 0 0 0 0 0 34 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _