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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGIF1
All Species:
4.55
Human Site:
S149
Identified Species:
11.11
UniProt:
Q15583
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.78
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15583
NP_003235.1
401
43013
S149
S
E
T
E
D
E
D
S
M
D
I
P
L
D
L
Chimpanzee
Pan troglodytes
Q5IS58
401
43063
S149
S
E
T
E
D
E
D
S
M
D
I
P
L
D
L
Rhesus Macaque
Macaca mulatta
Q8MID6
249
27534
R21
R
V
E
K
D
S
R
R
A
I
K
D
S
P
A
Dog
Lupus familis
XP_547659
272
29625
K44
R
R
R
G
N
L
P
K
E
S
V
Q
I
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P70284
272
29555
K44
R
R
R
G
N
L
P
K
E
S
V
Q
I
L
R
Rat
Rattus norvegicus
NP_001015020
287
31166
K59
R
R
R
G
N
L
P
K
E
S
V
Q
I
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510970
272
29089
K44
R
R
R
G
N
L
P
K
E
S
V
Q
I
L
R
Chicken
Gallus gallus
Q90655
269
29424
N41
G
K
R
R
R
R
G
N
L
P
K
E
S
V
Q
Frog
Xenopus laevis
NP_001080420
272
30006
K44
R
R
R
G
N
L
P
K
E
S
V
Q
I
L
R
Zebra Danio
Brachydanio rerio
NP_955861
273
29668
K45
K
R
R
G
N
L
P
K
E
S
V
Q
I
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
26.1
63.5
N.A.
60.8
61.8
N.A.
56.6
54.1
50.6
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
40.6
66
N.A.
64
66.3
N.A.
61.3
57.6
57.3
51.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
20
20
N.A.
20
20
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
30
0
20
0
0
20
0
10
0
20
0
% D
% Glu:
0
20
10
20
0
20
0
0
60
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
60
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
20
0
60
0
0
% I
% Lys:
10
10
0
10
0
0
0
60
0
0
20
0
0
0
0
% K
% Leu:
0
0
0
0
0
60
0
0
10
0
0
0
20
60
20
% L
% Met:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
60
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
60
0
0
10
0
20
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
10
% Q
% Arg:
60
60
70
10
10
10
10
10
0
0
0
0
0
0
60
% R
% Ser:
20
0
0
0
0
10
0
20
0
60
0
0
20
0
0
% S
% Thr:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
60
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _