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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TGIF1 All Species: 4.55
Human Site: S286 Identified Species: 11.11
UniProt: Q15583 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15583 NP_003235.1 401 43013 S286 P T L G R P L S P K P S S P G
Chimpanzee Pan troglodytes Q5IS58 401 43063 S286 P T L G R P L S P K P S S P G
Rhesus Macaque Macaca mulatta Q8MID6 249 27534 R143 D A H A T H L R S T D A S V P
Dog Lupus familis XP_547659 272 29625 I166 K P S S P G S I L A R P S V I
Cat Felis silvestris
Mouse Mus musculus P70284 272 29555 I166 K P P S P G S I L A R P S V I
Rat Rattus norvegicus NP_001015020 287 31166 I181 K P P S P G P I L A R P S V I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510970 272 29089 M166 K P S S P G S M L A R P S V I
Chicken Gallus gallus Q90655 269 29424 V163 K P V S P G S V L A R P S V I
Frog Xenopus laevis NP_001080420 272 30006 L166 K L S P P Q S L L A R P S V I
Zebra Danio Brachydanio rerio NP_955861 273 29668 P167 Y P K K A L S P K T P P S P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 26.1 63.5 N.A. 60.8 61.8 N.A. 56.6 54.1 50.6 44.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 40.6 66 N.A. 64 66.3 N.A. 61.3 57.6 57.3 51.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 6.6 N.A. 6.6 6.6 N.A. 6.6 6.6 6.6 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 6.6 N.A. 6.6 6.6 N.A. 6.6 13.3 6.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 10 0 0 0 0 60 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 20 0 50 0 0 0 0 0 0 0 0 30 % G
% His: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 30 0 0 0 0 0 0 60 % I
% Lys: 60 0 10 10 0 0 0 0 10 20 0 0 0 0 0 % K
% Leu: 0 10 20 0 0 10 30 10 60 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 20 60 20 10 60 20 10 10 20 0 30 70 0 30 10 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 20 0 0 10 0 0 60 0 0 0 0 % R
% Ser: 0 0 30 50 0 0 60 20 10 0 0 20 100 0 0 % S
% Thr: 0 20 0 0 10 0 0 0 0 20 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 10 0 0 0 0 0 70 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _