KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIXDC1
All Species:
22.73
Human Site:
S449
Identified Species:
55.56
UniProt:
Q155Q3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q155Q3
NP_001033043.1
683
77478
S449
E
E
A
L
R
K
L
S
D
V
S
Y
H
Q
V
Chimpanzee
Pan troglodytes
XP_001144981
683
77464
S449
E
E
A
L
R
K
L
S
D
V
S
Y
H
Q
V
Rhesus Macaque
Macaca mulatta
XP_001106684
683
77613
S449
E
E
A
L
R
K
L
S
D
A
S
Y
H
Q
V
Dog
Lupus familis
XP_862078
683
77413
S449
E
E
A
L
R
K
L
S
E
A
S
Y
Q
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y83
711
80196
S475
E
E
A
L
R
K
L
S
D
A
S
Y
Q
Q
V
Rat
Rattus norvegicus
Q2VUH7
674
76123
R437
K
D
L
G
Q
K
D
R
L
L
Q
Q
Q
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519634
389
42510
G192
E
P
Q
A
G
P
P
G
M
R
M
G
R
L
P
Chicken
Gallus gallus
XP_417934
681
77231
S447
D
E
M
L
R
Q
L
S
E
A
S
Y
Q
Q
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q804T6
443
50421
G246
E
S
Y
H
R
L
S
G
C
E
N
N
G
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796282
674
75641
S454
E
E
K
D
R
Q
A
S
D
I
S
R
Q
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.3
95.3
N.A.
87.9
85.3
N.A.
28.2
78.9
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
21.5
Protein Similarity:
100
99.5
98.9
97.8
N.A.
92.2
90.4
N.A.
37.7
85.9
N.A.
53.4
N.A.
N.A.
N.A.
N.A.
42
P-Site Identity:
100
100
93.3
80
N.A.
86.6
13.3
N.A.
6.6
60
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
40
N.A.
6.6
80
N.A.
20
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
10
0
0
10
0
0
40
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
0
0
10
0
50
0
0
0
0
0
0
% D
% Glu:
80
70
0
0
0
0
0
0
20
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
0
0
20
0
0
0
10
10
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
30
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
10
0
0
60
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
60
0
10
60
0
10
10
0
0
0
20
0
% L
% Met:
0
0
10
0
0
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% N
% Pro:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
10
0
10
20
0
0
0
0
10
10
50
70
0
% Q
% Arg:
0
0
0
0
80
0
0
10
0
10
0
10
10
0
0
% R
% Ser:
0
10
0
0
0
0
10
70
0
0
70
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
60
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
60
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _