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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIXDC1
All Species:
28.18
Human Site:
S546
Identified Species:
68.89
UniProt:
Q155Q3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q155Q3
NP_001033043.1
683
77478
S546
S
L
E
Q
G
I
S
S
L
M
E
R
L
H
V
Chimpanzee
Pan troglodytes
XP_001144981
683
77464
S546
S
L
E
Q
G
I
S
S
L
M
E
R
L
H
V
Rhesus Macaque
Macaca mulatta
XP_001106684
683
77613
S546
S
L
E
Q
G
I
S
S
L
M
E
R
L
H
V
Dog
Lupus familis
XP_862078
683
77413
S546
S
L
E
Q
G
I
S
S
L
M
E
R
L
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y83
711
80196
S574
S
L
E
Q
G
I
S
S
L
M
E
R
L
H
V
Rat
Rattus norvegicus
Q2VUH7
674
76123
S521
S
L
E
Q
G
I
S
S
L
I
E
R
L
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519634
389
42510
S276
P
Q
H
H
T
I
D
S
L
E
Q
G
I
S
S
Chicken
Gallus gallus
XP_417934
681
77231
S543
S
L
E
Q
G
I
S
S
L
M
E
R
L
H
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q804T6
443
50421
K330
S
T
R
S
P
G
R
K
A
N
H
T
D
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796282
674
75641
H545
G
K
L
E
G
H
L
H
N
P
D
R
P
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.3
95.3
N.A.
87.9
85.3
N.A.
28.2
78.9
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
21.5
Protein Similarity:
100
99.5
98.9
97.8
N.A.
92.2
90.4
N.A.
37.7
85.9
N.A.
53.4
N.A.
N.A.
N.A.
N.A.
42
P-Site Identity:
100
100
100
93.3
N.A.
100
93.3
N.A.
20
93.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
33.3
93.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% D
% Glu:
0
0
70
10
0
0
0
0
0
10
70
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
80
10
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
10
10
0
10
0
10
0
0
10
0
0
70
0
% H
% Ile:
0
0
0
0
0
80
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
70
10
0
0
0
10
0
80
0
0
0
70
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% N
% Pro:
10
0
0
0
10
0
0
0
0
10
0
0
10
0
0
% P
% Gln:
0
10
0
70
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
10
0
0
0
0
80
0
10
10
% R
% Ser:
80
0
0
10
0
0
70
80
0
0
0
0
0
20
20
% S
% Thr:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _