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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSN All Species: 47.88
Human Site: Y164 Identified Species: 81.03
UniProt: Q15631 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15631 NP_004613.1 228 26183 Y164 N S V T A G D Y S R P L H I S
Chimpanzee Pan troglodytes XP_001134810 223 25554 Y159 N S V T A G D Y S R P L H I S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540996 614 66425 Y550 N S V T A G D Y S R P L H I S
Cat Felis silvestris
Mouse Mus musculus Q62348 228 26182 Y164 N S V T A G D Y S R P L H I S
Rat Rattus norvegicus Q9JHB5 290 32987 I211 N S V G N G D I D T P F E V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521564 241 27394 Y177 N S V T A G D Y S R P L H I S
Chicken Gallus gallus P79769 229 25942 Y164 N S V T A G D Y S R P L R I S
Frog Xenopus laevis NP_001080426 228 26276 Y164 N S V I A G D Y S R P L R I A
Zebra Danio Brachydanio rerio NP_001020623 227 26149 Y164 N S V T A G D Y G R P L R I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610591 235 27007 Y165 N S V T M G D Y E R P L N I S
Honey Bee Apis mellifera XP_397233 234 27363 Y169 N S V T N G D Y N R P I E I A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781342 241 27362 Y166 N S V T S G D Y S R P I R I S
Poplar Tree Populus trichocarpa XP_002326362 239 27283 Y169 N Q V T A G D Y D C P R K V L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565857 308 35035 Y239 N R V T A G D Y D C P R K V M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 N.A. 36.8 N.A. 98.6 22.7 N.A. 83.8 86 78.9 78.9 N.A. 51 53.4 N.A. 55.1
Protein Similarity: 100 93.4 N.A. 36.9 N.A. 98.6 37.2 N.A. 89.2 92.1 88.5 85.9 N.A. 65.9 73 N.A. 73.8
P-Site Identity: 100 100 N.A. 100 N.A. 100 46.6 N.A. 100 93.3 80 86.6 N.A. 80 66.6 N.A. 80
P-Site Similarity: 100 100 N.A. 100 N.A. 100 53.3 N.A. 100 93.3 86.6 86.6 N.A. 86.6 86.6 N.A. 93.3
Percent
Protein Identity: 37.6 N.A. N.A. 28.9 N.A. N.A.
Protein Similarity: 55.2 N.A. N.A. 44.4 N.A. N.A.
P-Site Identity: 53.3 N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: 60 N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 72 0 0 0 0 0 0 0 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 100 0 22 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 0 0 0 15 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 8 0 100 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 % H
% Ile: 0 0 0 8 0 0 0 8 0 0 0 15 0 79 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 65 0 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 100 0 0 0 15 0 0 0 8 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 79 0 15 29 0 0 % R
% Ser: 0 86 0 0 8 0 0 0 58 0 0 0 0 0 72 % S
% Thr: 0 0 0 86 0 0 0 0 0 8 0 0 0 0 0 % T
% Val: 0 0 100 0 0 0 0 0 0 0 0 0 0 22 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _