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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED1
All Species:
25.45
Human Site:
S545
Identified Species:
50.91
UniProt:
Q15648
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15648
NP_004765.2
1581
168478
S545
K
N
L
P
P
A
S
S
P
G
Y
G
M
T
T
Chimpanzee
Pan troglodytes
XP_001172395
1581
168474
S545
K
N
L
P
P
A
S
S
P
G
Y
G
M
T
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537654
1583
168625
S545
K
N
L
P
P
A
S
S
P
G
Y
G
M
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q925J9
1575
167122
S545
K
N
L
P
P
A
S
S
P
G
Y
G
M
T
T
Rat
Rattus norvegicus
NP_001127833
1567
166392
S530
K
N
L
P
P
A
S
S
P
G
Y
G
M
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521297
422
46589
Chicken
Gallus gallus
XP_418125
1594
169410
S557
K
N
L
P
P
A
S
S
P
G
Y
G
M
T
T
Frog
Xenopus laevis
Q6INP8
1570
165663
L526
E
D
M
V
K
K
N
L
P
P
A
S
S
P
G
Zebra Danio
Brachydanio rerio
XP_700209
1694
176982
S532
K
N
L
P
P
T
G
S
P
G
Y
M
G
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP05
1475
149513
L475
L
A
T
V
D
F
L
L
E
D
G
Q
P
T
C
Honey Bee
Apis mellifera
XP_395879
1811
193227
N549
L
G
S
G
K
D
Q
N
S
Q
N
G
S
G
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786427
2421
258175
D567
P
S
G
G
S
V
F
D
P
M
S
G
L
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
98
N.A.
94.4
93.9
N.A.
24.4
87.6
72.5
56.4
N.A.
22
24.4
N.A.
25.7
Protein Similarity:
100
100
N.A.
98.9
N.A.
97.1
96.5
N.A.
25.7
93.5
81.7
69
N.A.
38.9
41.1
N.A.
38.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
0
100
6.6
60
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
0
100
33.3
60
N.A.
6.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
50
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
9
0
0
9
9
0
9
0
9
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
17
0
0
9
0
0
59
9
67
9
9
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
59
0
0
0
17
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
0
59
0
0
0
9
17
0
0
0
0
9
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
9
0
9
50
9
9
% M
% Asn:
0
59
0
0
0
0
9
9
0
0
9
0
0
0
0
% N
% Pro:
9
0
0
59
59
0
0
0
75
9
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
9
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
9
9
0
9
0
50
59
9
0
9
9
17
0
0
% S
% Thr:
0
0
9
0
0
9
0
0
0
0
0
0
0
59
50
% T
% Val:
0
0
0
17
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _