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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNHIT3 All Species: 4.24
Human Site: S73 Identified Species: 7.78
UniProt: Q15649 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15649 NP_004764.1 155 17607 S73 E N K D D D D S I A D F L N S
Chimpanzee Pan troglodytes Q6UIM2 141 16122 S74 D E E E D R V S L Q N L K N L
Rhesus Macaque Macaca mulatta Q6UIM1 147 16695 E74 A D F L N S D E E E D R V S L
Dog Lupus familis XP_537712 156 17608 E73 E N K D D D E E S V A D F L N
Cat Felis silvestris
Mouse Mus musculus Q9CQK1 151 17049 F73 D D S S V A D F L N S D E E E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510518 300 33368 K220 P L E D K G D K W S A L L T S
Chicken Gallus gallus
Frog Xenopus laevis NP_001091379 145 16676 R73 D E D N E S D R V P P H K L K
Zebra Danio Brachydanio rerio NP_956567 151 17040 D74 L D E D S Q T D K V P L Q R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611050 143 16271 Q75 V A A E K L Q Q L E N C Q E L
Honey Bee Apis mellifera XP_001120685 135 15551 K71 E D T V S V E K L K Q L R H S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002301830 154 16910 S78 L L K L Q L E S I D N W S G L
Maize Zea mays NP_001152218 169 19015 H73 K C P N D K D H P S L S L H T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P46973 164 18358 A78 N K T L K T K A F D D I Y Q N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 91.6 87.1 N.A. 78.7 N.A. N.A. 28.3 N.A. 45.1 50.3 N.A. 38 36.7 N.A. N.A.
Protein Similarity: 100 90.3 92.9 92.9 N.A. 87 N.A. N.A. 37.3 N.A. 60 65.1 N.A. 55.4 53.5 N.A. N.A.
P-Site Identity: 100 20 13.3 40 N.A. 6.6 N.A. N.A. 26.6 N.A. 6.6 6.6 N.A. 0 13.3 N.A. N.A.
P-Site Similarity: 100 53.3 40 53.3 N.A. 26.6 N.A. N.A. 40 N.A. 33.3 20 N.A. 20 40 N.A. N.A.
Percent
Protein Identity: 32.9 33.1 N.A. N.A. 21.3 N.A.
Protein Similarity: 49 47.3 N.A. N.A. 39.6 N.A.
P-Site Identity: 20 20 N.A. N.A. 6.6 N.A.
P-Site Similarity: 40 53.3 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 8 0 8 0 8 16 0 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 24 31 8 31 31 16 47 8 0 16 24 16 0 0 0 % D
% Glu: 24 16 24 16 8 0 24 16 8 16 0 0 8 16 8 % E
% Phe: 0 0 8 0 0 0 0 8 8 0 0 8 8 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 8 0 16 0 % H
% Ile: 0 0 0 0 0 0 0 0 16 0 0 8 0 0 0 % I
% Lys: 8 8 24 0 24 8 8 16 8 8 0 0 16 0 8 % K
% Leu: 16 16 0 24 0 16 0 0 31 0 8 31 24 16 39 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 16 0 16 8 0 0 0 0 8 24 0 0 16 16 % N
% Pro: 8 0 8 0 0 0 0 0 8 8 16 0 0 0 0 % P
% Gln: 0 0 0 0 8 8 8 8 0 8 8 0 16 8 0 % Q
% Arg: 0 0 0 0 0 8 0 8 0 0 0 8 8 8 0 % R
% Ser: 0 0 8 8 16 16 0 24 8 16 8 8 8 8 24 % S
% Thr: 0 0 16 0 0 8 8 0 0 0 0 0 0 8 8 % T
% Val: 8 0 0 8 8 8 8 0 8 16 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _