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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNHIT3
All Species:
8.18
Human Site:
Y130
Identified Species:
15
UniProt:
Q15649
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15649
NP_004764.1
155
17607
Y130
K
A
K
L
M
R
A
Y
M
Q
E
P
L
F
V
Chimpanzee
Pan troglodytes
Q6UIM2
141
16122
L121
R
A
Y
M
Q
E
P
L
F
V
E
F
A
D
C
Rhesus Macaque
Macaca mulatta
Q6UIM1
147
16695
Y122
K
A
K
L
M
R
A
Y
M
Q
E
P
L
F
V
Dog
Lupus familis
XP_537712
156
17608
C131
K
A
K
L
M
R
A
C
M
Q
E
P
L
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQK1
151
17049
C126
K
A
K
L
M
R
A
C
M
Q
E
P
L
F
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510518
300
33368
Y277
K
E
V
L
M
K
R
Y
M
Q
E
P
L
F
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091379
145
16676
M118
E
D
A
M
K
K
Y
M
Q
E
P
L
F
V
E
Zebra Danio
Brachydanio rerio
NP_956567
151
17040
A119
K
A
K
A
M
K
D
A
M
Q
E
P
L
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611050
143
16271
F120
Q
E
P
L
F
V
E
F
A
N
A
C
L
Q
V
Honey Bee
Apis mellifera
XP_001120685
135
15551
F116
L
A
M
T
E
P
I
F
V
E
M
A
D
A
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301830
154
16910
E131
C
S
T
D
P
E
S
E
L
D
V
A
M
G
V
Maize
Zea mays
NP_001152218
169
19015
A122
E
L
K
G
I
H
D
A
L
R
D
P
E
L
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46973
164
18358
D124
S
S
G
K
M
N
S
D
L
Q
K
E
L
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
91.6
87.1
N.A.
78.7
N.A.
N.A.
28.3
N.A.
45.1
50.3
N.A.
38
36.7
N.A.
N.A.
Protein Similarity:
100
90.3
92.9
92.9
N.A.
87
N.A.
N.A.
37.3
N.A.
60
65.1
N.A.
55.4
53.5
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
N.A.
N.A.
73.3
N.A.
0
73.3
N.A.
20
6.6
N.A.
N.A.
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
N.A.
N.A.
80
N.A.
26.6
80
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
32.9
33.1
N.A.
N.A.
21.3
N.A.
Protein Similarity:
49
47.3
N.A.
N.A.
39.6
N.A.
P-Site Identity:
6.6
13.3
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
33.3
46.6
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
8
8
0
0
31
16
8
0
8
16
8
16
0
% A
% Cys:
8
0
0
0
0
0
0
16
0
0
0
8
0
0
16
% C
% Asp:
0
8
0
8
0
0
16
8
0
8
8
0
8
8
0
% D
% Glu:
16
16
0
0
8
16
8
8
0
16
54
8
8
0
8
% E
% Phe:
0
0
0
0
8
0
0
16
8
0
0
8
8
47
0
% F
% Gly:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
47
0
47
8
8
24
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
8
0
47
0
0
0
8
24
0
0
8
62
8
0
% L
% Met:
0
0
8
16
54
0
0
8
47
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
8
8
0
0
0
8
54
0
0
0
% P
% Gln:
8
0
0
0
8
0
0
0
8
54
0
0
0
8
8
% Q
% Arg:
8
0
0
0
0
31
8
0
0
8
0
0
0
0
0
% R
% Ser:
8
16
0
0
0
0
16
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
8
0
0
8
8
8
0
0
8
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _