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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIP4
All Species:
38.79
Human Site:
S533
Identified Species:
71.11
UniProt:
Q15650
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15650
NP_057297.2
581
66146
S533
F
P
D
I
S
Q
E
S
D
S
P
F
V
F
I
Chimpanzee
Pan troglodytes
XP_510472
581
66144
S533
F
P
D
I
S
Q
E
S
D
S
P
Y
V
F
I
Rhesus Macaque
Macaca mulatta
XP_001107836
581
66108
S533
F
P
D
I
S
Q
E
S
D
S
P
F
V
F
I
Dog
Lupus familis
XP_535513
581
66444
S533
Y
P
D
M
S
Q
E
S
D
S
P
F
V
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXN3
581
66189
S533
F
P
D
I
S
Q
E
S
D
S
S
F
V
F
I
Rat
Rattus norvegicus
NP_001128453
581
65833
S533
F
P
D
I
S
Q
E
S
D
S
P
F
V
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509179
577
65839
S529
H
P
D
L
S
Q
E
S
D
S
P
F
V
Y
L
Chicken
Gallus gallus
XP_413717
620
69438
S572
Y
P
D
L
S
Q
E
S
G
S
P
F
V
F
I
Frog
Xenopus laevis
NP_001085378
567
64726
S523
Y
P
S
M
N
Q
E
S
G
S
P
F
V
F
I
Zebra Danio
Brachydanio rerio
NP_001071043
564
64113
S519
Y
P
Q
I
S
E
E
S
T
S
P
F
V
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608393
513
57746
H488
L
L
P
V
H
G
D
H
K
I
Y
E
L
P
L
Honey Bee
Apis mellifera
XP_624783
476
55388
K452
Q
G
N
H
K
I
Y
K
L
N
R
K
I
H
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787043
567
63930
C527
S
S
P
Y
V
F
I
C
E
N
P
Q
E
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.9
90.5
N.A.
88.8
88.6
N.A.
77.2
65.6
61
58
N.A.
32.8
37.6
N.A.
43.8
Protein Similarity:
100
100
99.1
95.5
N.A.
93.6
93.2
N.A.
86.9
77.9
76.2
76
N.A.
54.9
56.9
N.A.
62.6
P-Site Identity:
100
93.3
100
86.6
N.A.
93.3
100
N.A.
73.3
80
66.6
73.3
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
93.3
93.3
86.6
86.6
N.A.
26.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
62
0
0
0
8
0
54
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
77
0
8
0
0
8
8
0
0
% E
% Phe:
39
0
0
0
0
8
0
0
0
0
0
70
0
70
8
% F
% Gly:
0
8
0
0
0
8
0
0
16
0
0
0
0
0
0
% G
% His:
8
0
0
8
8
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
47
0
8
8
0
0
8
0
0
8
0
70
% I
% Lys:
0
0
0
0
8
0
0
8
8
0
0
8
0
0
0
% K
% Leu:
8
8
0
16
0
0
0
0
8
0
0
0
8
8
16
% L
% Met:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
16
0
0
0
0
0
% N
% Pro:
0
77
16
0
0
0
0
0
0
0
77
0
0
8
0
% P
% Gln:
8
0
8
0
0
70
0
0
0
0
0
8
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
8
8
8
0
70
0
0
77
0
77
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
0
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
31
0
0
8
0
0
8
0
0
0
8
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _