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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFKBIB
All Species:
13.64
Human Site:
Y180
Identified Species:
30
UniProt:
Q15653
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15653
NP_001001716.1
356
37771
Y180
N
H
T
P
V
A
L
Y
P
D
S
D
L
E
K
Chimpanzee
Pan troglodytes
XP_001168499
356
37628
Y180
N
H
T
P
V
A
L
Y
P
D
S
D
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001085582
356
37504
Y180
N
H
T
P
V
A
L
Y
P
D
S
D
L
E
K
Dog
Lupus familis
XP_541633
357
37644
Y180
D
H
P
P
V
A
S
Y
P
E
P
D
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60778
359
37982
D180
S
H
A
P
A
A
V
D
S
Q
P
N
P
E
N
Rat
Rattus norvegicus
Q9JIA3
359
38063
D180
S
H
A
P
V
A
T
D
P
Q
P
N
P
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519324
329
36001
Y196
A
V
L
Q
A
S
N
Y
N
G
H
T
C
L
H
Chicken
Gallus gallus
Q91974
318
35380
Y185
A
V
L
Q
A
T
N
Y
N
G
H
T
C
L
H
Frog
Xenopus laevis
NP_001089595
349
37854
L217
H
L
Q
N
W
K
G
L
S
C
L
H
I
A
T
Zebra Danio
Brachydanio rerio
NP_001122267
394
43278
G186
Q
C
L
L
Q
N
I
G
M
D
N
T
W
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03017
500
53800
L346
N
D
K
A
V
S
S
L
S
Y
A
C
L
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.1
89.6
N.A.
83.8
81.6
N.A.
25.2
21.3
21
20
N.A.
20.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97.7
94.1
N.A.
88.3
87.1
N.A.
38.7
33.9
36.5
31.2
N.A.
32.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
26.6
33.3
N.A.
6.6
6.6
0
6.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
46.6
46.6
N.A.
13.3
6.6
13.3
20
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
19
10
28
55
0
0
0
0
10
0
0
10
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
10
0
10
19
0
0
% C
% Asp:
10
10
0
0
0
0
0
19
0
37
0
37
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
0
46
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
10
0
19
0
0
0
10
0
% G
% His:
10
55
0
0
0
0
0
0
0
0
19
10
0
0
19
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% I
% Lys:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
37
% K
% Leu:
0
10
28
10
0
0
28
19
0
0
10
0
46
19
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
37
0
0
10
0
10
19
0
19
0
10
19
0
0
19
% N
% Pro:
0
0
10
55
0
0
0
0
46
0
28
0
19
10
10
% P
% Gln:
10
0
10
19
10
0
0
0
0
19
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
19
0
0
0
0
19
19
0
28
0
28
0
0
0
0
% S
% Thr:
0
0
28
0
0
10
10
0
0
0
0
28
0
0
10
% T
% Val:
0
19
0
0
55
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _