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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIP6
All Species:
23.94
Human Site:
S440
Identified Species:
43.89
UniProt:
Q15654
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15654
NP_003293.2
476
50288
S440
E
E
C
G
L
L
L
S
S
E
G
E
C
Q
G
Chimpanzee
Pan troglodytes
XP_001159438
612
65827
S577
E
D
C
G
G
L
L
S
E
G
D
N
Q
G
C
Rhesus Macaque
Macaca mulatta
XP_001106127
476
50267
S440
E
E
C
G
L
L
L
S
S
E
G
E
C
Q
G
Dog
Lupus familis
XP_536859
478
50671
S442
E
E
C
G
L
L
L
S
S
E
G
E
C
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Y4
480
50915
S444
E
E
C
G
L
L
L
S
S
E
G
E
C
Q
G
Rat
Rattus norvegicus
Q5XI07
632
68242
S597
E
D
C
G
G
L
L
S
E
G
D
N
Q
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506023
531
55801
A495
A
P
R
C
S
V
C
A
G
A
I
M
P
E
P
Chicken
Gallus gallus
Q5F464
604
65121
S569
E
D
C
G
G
L
L
S
E
G
D
N
Q
G
C
Frog
Xenopus laevis
A5H447
663
70707
A600
C
V
C
G
D
P
I
A
P
E
P
G
R
D
E
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
N605
E
D
C
G
L
Q
L
N
D
E
E
G
H
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396072
477
52619
S441
E
D
C
G
L
I
L
S
S
D
S
E
G
R
G
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
R378
K
F
H
P
E
H
F
R
C
S
Y
C
N
H
Q
Sea Urchin
Strong. purpuratus
XP_798292
448
48550
L400
E
T
V
R
I
V
A
L
D
R
S
F
H
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.1
98.3
89.3
N.A.
86.4
41.7
N.A.
58.5
43.3
30.4
28.7
N.A.
N.A.
36.6
21.4
39.9
Protein Similarity:
100
53.7
98.5
92.2
N.A.
90.2
51.2
N.A.
64.2
53.1
42.6
42.7
N.A.
N.A.
49
35.7
51.6
P-Site Identity:
100
40
100
100
N.A.
100
40
N.A.
0
40
20
40
N.A.
N.A.
60
0
6.6
P-Site Similarity:
100
46.6
100
100
N.A.
100
46.6
N.A.
20
46.6
33.3
60
N.A.
N.A.
86.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
16
0
8
0
0
0
0
0
% A
% Cys:
8
0
77
8
0
0
8
0
8
0
0
8
31
0
31
% C
% Asp:
0
39
0
0
8
0
0
0
16
8
24
0
0
8
0
% D
% Glu:
77
31
0
0
8
0
0
0
24
47
8
39
0
8
8
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
77
24
0
0
0
8
24
31
16
8
24
39
% G
% His:
0
0
8
0
0
8
0
0
0
0
0
0
16
8
8
% H
% Ile:
0
0
0
0
8
8
8
0
0
0
8
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
47
54
70
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
24
8
0
0
% N
% Pro:
0
8
0
8
0
8
0
0
8
0
8
0
8
0
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
24
31
8
% Q
% Arg:
0
0
8
8
0
0
0
8
0
8
0
0
8
16
0
% R
% Ser:
0
0
0
0
8
0
0
62
39
8
16
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
8
0
0
16
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _