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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIP6
All Species:
25.45
Human Site:
Y275
Identified Species:
46.67
UniProt:
Q15654
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15654
NP_003293.2
476
50288
Y275
N
H
P
P
S
G
E
Y
F
G
Q
C
G
G
C
Chimpanzee
Pan troglodytes
XP_001159438
612
65827
Y412
E
N
P
P
A
D
E
Y
F
G
R
C
A
R
C
Rhesus Macaque
Macaca mulatta
XP_001106127
476
50267
Y275
N
H
P
P
S
G
E
Y
F
G
Q
C
G
G
C
Dog
Lupus familis
XP_536859
478
50671
Y277
N
H
P
P
T
G
E
Y
F
G
R
C
G
G
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Y4
480
50915
Y279
S
H
P
P
S
G
E
Y
F
G
R
C
G
G
C
Rat
Rattus norvegicus
Q5XI07
632
68242
Y432
E
N
P
P
A
D
D
Y
F
G
R
C
A
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506023
531
55801
E345
P
P
S
R
P
P
E
E
E
V
E
R
L
T
K
Chicken
Gallus gallus
Q5F464
604
65121
Y404
E
N
P
P
S
D
D
Y
F
G
R
C
A
R
C
Frog
Xenopus laevis
A5H447
663
70707
H421
I
H
R
T
G
G
Q
H
S
G
H
K
V
T
G
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
Y435
E
I
H
M
K
K
E
Y
F
G
I
C
V
K
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396072
477
52619
I279
E
D
N
D
I
Y
G
I
C
A
Q
C
G
R
K
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
P233
D
Y
H
N
Q
F
S
P
K
C
Q
G
C
H
R
Sea Urchin
Strong. purpuratus
XP_798292
448
48550
G251
G
T
T
Q
E
P
E
G
E
F
F
G
M
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.1
98.3
89.3
N.A.
86.4
41.7
N.A.
58.5
43.3
30.4
28.7
N.A.
N.A.
36.6
21.4
39.9
Protein Similarity:
100
53.7
98.5
92.2
N.A.
90.2
51.2
N.A.
64.2
53.1
42.6
42.7
N.A.
N.A.
49
35.7
51.6
P-Site Identity:
100
53.3
100
86.6
N.A.
86.6
46.6
N.A.
6.6
53.3
20
40
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
100
73.3
100
100
N.A.
100
73.3
N.A.
13.3
73.3
33.3
40
N.A.
N.A.
20
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
0
0
0
8
0
0
24
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
8
0
70
8
8
62
% C
% Asp:
8
8
0
8
0
24
16
0
0
0
0
0
0
0
0
% D
% Glu:
39
0
0
0
8
0
62
8
16
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
62
8
8
0
0
0
0
% F
% Gly:
8
0
0
0
8
39
8
8
0
70
0
16
39
31
8
% G
% His:
0
39
16
0
0
0
0
8
0
0
8
0
0
8
0
% H
% Ile:
8
8
0
0
8
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
8
8
0
0
8
0
0
8
0
8
16
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
24
24
8
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
54
54
8
16
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
0
8
0
0
0
31
0
0
0
0
% Q
% Arg:
0
0
8
8
0
0
0
0
0
0
39
8
0
31
8
% R
% Ser:
8
0
8
0
31
0
8
0
8
0
0
0
0
0
8
% S
% Thr:
0
8
8
8
8
0
0
0
0
0
0
0
0
16
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _