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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWIST1
All Species:
14.85
Human Site:
S174
Identified Species:
25.13
UniProt:
Q15672
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15672
NP_000465.1
202
20954
S174
E
L
D
S
K
M
A
S
C
S
Y
V
A
H
E
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
M173
S
D
E
L
D
S
K
M
A
S
Y
V
A
H
E
Rhesus Macaque
Macaca mulatta
XP_001103003
192
19946
C165
L
D
S
K
M
A
S
C
S
Y
V
A
H
E
R
Dog
Lupus familis
XP_862829
199
20704
S171
E
L
D
S
K
M
A
S
C
S
Y
V
A
H
E
Cat
Felis silvestris
Mouse
Mus musculus
P26687
206
21180
S178
E
L
D
S
K
M
A
S
C
S
Y
V
A
H
E
Rat
Rattus norvegicus
P97831
160
18106
C133
M
D
N
K
M
T
S
C
S
Y
V
A
H
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510876
214
24100
S186
E
M
D
N
K
M
T
S
C
S
Y
V
A
H
E
Chicken
Gallus gallus
NP_990070
190
20385
C163
L
D
S
K
M
A
S
C
S
Y
V
A
H
E
R
Frog
Xenopus laevis
P13903
166
18778
C139
L
D
S
K
M
A
S
C
S
Y
V
A
H
E
R
Zebra Danio
Brachydanio rerio
Q7ZSX3
265
30428
H181
D
M
P
I
R
N
P
H
S
D
A
L
N
Q
P
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
S271
D
G
G
R
N
V
S
S
T
T
D
G
E
T
G
Fruit Fly
Dros. melanogaster
P10627
490
54403
L428
D
I
S
L
L
K
A
L
E
A
Q
G
S
P
S
Honey Bee
Apis mellifera
NP_001011637
366
42484
D319
M
E
N
T
E
G
A
D
D
A
S
E
R
N
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001099179
204
23479
G175
E
E
D
Q
K
M
V
G
S
C
N
Y
M
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
94
98.5
N.A.
95.1
66.3
N.A.
52.3
88.6
70.7
21.8
21.8
23.4
32.5
N.A.
46.5
Protein Similarity:
100
98
94
98.5
N.A.
95.6
72.7
N.A.
62.6
89.1
76.7
34.3
31.8
28.7
39.8
N.A.
55.3
P-Site Identity:
100
40
0
100
N.A.
100
0
N.A.
80
0
0
0
6.6
6.6
6.6
N.A.
26.6
P-Site Similarity:
100
46.6
6.6
100
N.A.
100
13.3
N.A.
93.3
6.6
6.6
26.6
33.3
33.3
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
22
36
0
8
15
8
29
36
8
0
% A
% Cys:
0
0
0
0
0
0
0
29
29
8
0
0
0
0
0
% C
% Asp:
22
36
36
0
8
0
0
8
8
8
8
0
0
0
0
% D
% Glu:
36
15
8
0
8
0
0
0
8
0
0
8
8
29
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
8
0
8
0
0
0
15
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
29
36
8
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
29
36
8
8
0
0
0
0
0
0
0
0
% K
% Leu:
22
22
0
15
8
0
0
8
0
0
0
8
0
0
0
% L
% Met:
15
15
0
0
29
36
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
15
8
8
8
0
0
0
0
8
0
8
8
0
% N
% Pro:
0
0
8
0
0
0
8
0
0
0
0
0
0
8
15
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
29
% R
% Ser:
8
0
29
22
0
8
36
36
43
36
8
0
8
0
8
% S
% Thr:
0
0
0
8
0
8
8
0
8
8
0
0
0
8
0
% T
% Val:
0
0
0
0
0
8
8
0
0
0
29
36
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
29
36
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _