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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWIST1
All Species:
6.67
Human Site:
S68
Identified Species:
11.28
UniProt:
Q15672
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15672
NP_000465.1
202
20954
S68
G
G
G
D
E
P
G
S
P
A
Q
G
K
R
G
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
G67
V
G
G
G
D
E
P
G
S
P
A
Q
G
K
R
Rhesus Macaque
Macaca mulatta
XP_001103003
192
19946
S59
G
G
G
D
E
P
G
S
P
A
Q
G
K
R
G
Dog
Lupus familis
XP_862829
199
20704
E65
G
G
V
G
G
G
D
E
P
G
S
P
A
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
P26687
206
21180
G72
E
P
G
S
P
A
Q
G
K
R
G
K
K
S
A
Rat
Rattus norvegicus
P97831
160
18106
K27
E
E
L
E
R
Q
P
K
R
F
G
R
K
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510876
214
24100
P80
E
E
E
L
E
R
Q
P
K
R
F
G
R
K
R
Chicken
Gallus gallus
NP_990070
190
20385
P57
A
V
G
A
A
D
E
P
C
S
P
A
Q
G
K
Frog
Xenopus laevis
P13903
166
18778
R33
Q
Q
S
K
R
G
C
R
K
R
R
S
A
R
K
Zebra Danio
Brachydanio rerio
Q7ZSX3
265
30428
S75
D
V
G
N
F
S
F
S
S
S
S
S
T
F
S
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
P165
M
L
Y
N
L
A
Q
P
L
A
A
I
N
S
L
Fruit Fly
Dros. melanogaster
P10627
490
54403
D322
M
S
P
A
C
L
A
D
D
G
S
A
G
S
L
Honey Bee
Apis mellifera
NP_001011637
366
42484
N213
Y
V
L
E
G
P
R
N
G
K
R
K
R
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001099179
204
23479
S69
R
K
R
R
F
R
Q
S
E
G
E
D
E
C
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
94
98.5
N.A.
95.1
66.3
N.A.
52.3
88.6
70.7
21.8
21.8
23.4
32.5
N.A.
46.5
Protein Similarity:
100
98
94
98.5
N.A.
95.6
72.7
N.A.
62.6
89.1
76.7
34.3
31.8
28.7
39.8
N.A.
55.3
P-Site Identity:
100
13.3
100
26.6
N.A.
13.3
13.3
N.A.
13.3
6.6
6.6
13.3
6.6
0
6.6
N.A.
6.6
P-Site Similarity:
100
26.6
100
33.3
N.A.
13.3
20
N.A.
26.6
20
13.3
26.6
13.3
0
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
8
15
8
0
0
22
15
15
15
0
8
% A
% Cys:
0
0
0
0
8
0
8
0
8
0
0
0
0
8
0
% C
% Asp:
8
0
0
15
8
8
8
8
8
0
0
8
0
0
0
% D
% Glu:
22
15
8
15
22
8
8
8
8
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
15
0
8
0
0
8
8
0
0
8
0
% F
% Gly:
22
29
43
15
15
15
15
15
8
22
15
22
15
8
22
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
0
8
0
0
0
8
22
8
0
15
29
22
15
% K
% Leu:
0
8
15
8
8
8
0
0
8
0
0
0
0
0
15
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
8
8
0
8
22
15
22
22
8
8
8
0
0
0
% P
% Gln:
8
8
0
0
0
8
29
0
0
0
15
8
8
8
8
% Q
% Arg:
8
0
8
8
15
15
8
8
8
22
15
8
15
29
22
% R
% Ser:
0
8
8
8
0
8
0
29
15
15
22
15
0
22
15
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
8
22
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _